自拟清肝降压饮早期干预高血压前期和原发性1级高血压  

Clinical Research on Early Intervention of Pre-hypertension and Primary Grade 1 Hypertension by Qinggan Jiangya Drink

作　　者：李逊[1] 魏玲[2] 

机构地区：[1]遵义医学院第一附属医院,贵州遵义563003 [2]云南省第二人民医院,昆明650021

出　　处：《中国实验方剂学杂志》2013年第3期295-297,共3页Chinese Journal of Experimental Traditional Medical Formulae

摘　　要：目的:探讨自拟清肝降压饮早期干预高血压前期和原发性1级高血压的临床疗效。方法:将146例高血压前期和原发性1级高血压患者随机分为治疗组和对照组各73例,对照组采用非药物干预方式,治疗组在非药物干预方式基础上加用清肝降压饮代茶饮,2～4剂/d,疗程8周。观察血压控制情况、中医临床症状、检测治疗前后血脂。结果:治疗4,8周及治疗结束后4周治疗组血压均低于对照组(P<0.01);治疗4周和8周治疗组血压复常率分别为43.83%和90.41%,均明显优于同期对照组(P<0.01);治疗后治疗组血压总有效率为95.89%,优于对照组的60.27%(P<0.01);治疗后治疗组证候总有效率98.63%,优于对照的56.16%(P<0.01);治疗组对患者血脂有明显的调节作用。结论:在"治未病"的思想指导下,中药早期干预高血压前期和原发性1级高血压有较好的临床疗效。Objective： To study the clinical curative effect of Qinggan Jiangya drink （QJD） for early intervention of pre-hypertension and primary grade 1 hypertension. Method： One hundred and forty-six patients with hypertension and the primary grade 1 hypertension were randomly divided into treatment group and control group （n = 73, each） , control group was in non drug intervention mode, the treatment group was given QJD 2 -4 agent daily for 8 weeks. Blood pressure, blood lipids and scores of traditional Chinese medicine syndromes were observed before and after treatment. Result： Blood pressure after 4 and 8 weeks of treatment and that after another 4 weeks in treatment group wag lower than those of the control group （P 〈 0.01 ）. The recovery rate of blood pressure after treatment of 4 weeks and 8 weeks were 43.83% and 90.41% respectively, all was better than the control group （P 〈0.01 ）. The total effective rate of blood pressure in the treatment group was 95.89% , which is higher than that of 60.27% in control group （P 〈 0.01 ）. After treatment, the total effective rate for the scores of syndromes was 98.63% , in the treatment group, while 56. 16% in the controls （P 〈 0.01 ）. The treatment also showed significant regulation for blood lipids. Conclusion： The clinical curative effect of early intervention for pre- hypertension and primary grade 1 hypertension by traditional Chinese medicine is promising. This is gained under the guidance of the principle of ＇ preventive intervention before a formed disease＇

关 键 词：高血压前期 1级高血压 清肝降压饮 治未病 

分 类 号：R287[医药卫生—中药学]