室壁中层缩短率评价早期2型糖尿病患者左室收缩功能的价值  

Evaluation of left cardiac function in patients with early-stage type 2 diabetes mellitus by midwall fractional shortening

作　　者：王全江[1] 张煜华[1] 车正兰[2] 韩宗耀[1] 王燕华[1] 

机构地区：[1]郑州市第三人民医院超声科,450000 [2]贵阳医学院附属医院超声科

出　　处：《临床超声医学杂志》2013年第1期48-50,共3页Journal of Clinical Ultrasound in Medicine

基　　金：郑州市2010年度科技攻关项目(2010SFXM175)

摘　　要：目的使用超声心动图多种指标全面评价2型糖尿病患者左心结构及其功能,从中筛选敏感指标。方法对24例2型糖尿病患者(糖尿病组)和30例健康志愿者(正常对照组)进行超声心动图检查,测定左房、左室、左室质量指数、射血分数、短轴缩短率、室壁中层缩短率(MFS)、等容舒张时间、二尖瓣口舒张早期峰值流速、二尖瓣口舒张晚期峰值流速、二尖瓣环舒张早期运动峰值速度(Em)及二尖瓣环舒张晚期运动峰值速度(Am)等指标。结果与正常对照组比较,糖尿病组舒张功能指标中,Em和Em/Am显著降低(P﹤0.05),收缩功能指标中,除MFS外,其余均无统计学意义。结论早期2型糖尿病患者不仅左室舒张功能有不同程度的减退,而且已经出现心肌收缩功能损害,MFS是评价左室收缩功能的敏感指标。Objective To evaluate left ventricular （LV）structure and function in patients with type 2 diabetes mellitus （T2DM）by echocardiography.Methods Echocardiography was performed in 24 patients with T2DM and 30 healthy normal subjects.The echocardiographie parameters were analyzed,including LV diameter,left atrial diameter,LV mass index, LV eject fraction, LV fractional shortening, midwall fractional shortening （ MFS ）, early diastolic mitral inflow velocity, later diastolic mitral inflow velocity, mitral annular early diastolic velocity （Em） and mitral annular later diastolic velocity （Am）.Results There were no significant difference in left systolic function except MFS between patients with T2DM and normal subjects.However, Em and Em/Am decreased significantly in patients with T2DM.Conclusion Both diastolic function and systolic function have been damaged in early diabetic cardiomyopathy, MFS is a sensitive index in evaluating LV systolic function.

关 键 词：糖尿病 2型 超声心动描记术 收缩功能 室壁中层缩短率 心室 左 

分 类 号：R540.5[医药卫生—心血管疾病] R445.1[医药卫生—内科学]