丙型肝炎病毒感染与2型糖尿病发病关系的研究  

The association between hepatitis c virus infection and type 2 diabetes

作　　者：韦艳妮[1] 梁能秀[1] 苏齐鉴[2] 徐斌[3] 何晓[1] 徐世民[1] 谢志春[1] 

机构地区：[1]广西医科大学公共卫生学院流行病学教研室,广西南宁530021 [2]广西中医学院附属瑞康医院,广西南宁530021 [3]广西南宁市疾病预防控制中心,广西南宁530021

出　　处：《热带医学杂志》2013年第1期17-19,共3页Journal of Tropical Medicine

摘　　要：目的通过调查2型糖尿病患者中丙型肝炎病毒抗体(抗-HCV)的流行情况,探索HCV感染是否为2型糖尿病发病的危险因素。方法采用酶联免疫法(ELISA)对710例2型糖尿病患者与696例非糖尿病者(对照组)的血清进行抗-HCV检测,并进行比较。结果 2型糖尿病组的抗-HCV阳性率(3.10%)明显高于对照组的阳性率(1.29%),两者比较差异有统计学意义(χ2=5.313,P<0.05)。但在所有年龄组中,只有60～69岁年龄组中两者比较差异有统计学意义(χ2=6.891,P<0.01)。2型糖尿病组与对照组之间比值比(OR)为2.44(95%CI1.14-5.21)。结论 HCV感染可能是2型糖尿病发病的危险因素之一。Objective The risk of diabetes was studied through the investigation of the prevalence of anti-hepatitis C virus antibody （anti-HCV） in the patients with type 2 diabetes. Methods 710 cases of type 2 diabetes and 696 cases of control subjects were included in this study. Enzyme-linked immunosorbent assay （ELISA） was used in the determination of anti-HCV antibody. Results The anti-HCV positive rate in the type 2 diabetes group （3.10%） was significantly higher than the control group （1.29%） （χ2=5.313,P〈 0.05）. Significant difference was also observed in the age group of 60-69 （χ2=6.891,P〈 0.01）. The odds ratio（OR） in type 2 diabetes group and eontrol group was 1.44 （95% CI 1.14-5.21）. Conclusion HCV may be one of the risk factors for type 2 diabetes.

关 键 词：丙型肝炎病毒 2型糖尿病 阳性率 

分 类 号：R512.63[医药卫生—内科学] R587.1[医药卫生—临床医学]