麝香祛痛气雾剂治疗急性软组织损伤(气滞血瘀证)的临床研究  

The clinical research of Moschus Analgesic Aerosol s therapeutic effects on acute soft tissue injury

作　　者：李成刚[1] 周丽[2] 沈霖[1] 杨艳萍[1] 

机构地区：[1]华中科技大学同济医学院附属协和医院中西医结合科,武汉430022 [2]华中科技大学同济医学院附属同济医院中西医结合科

出　　处：《中国中医骨伤科杂志》2013年第2期23-25,共3页Chinese Journal of Traditional Medical Traumatology & Orthopedics

摘　　要：目的:以云南白药气雾剂为对照,科学地评价麝香祛痛气雾剂的临床疗效及安全性。方法:采用随机、双盲、阳性药物平行对照的方法将281例急性软组织损伤(气滞血瘀证)患者随机分为麝香祛痛气雾剂治疗组(209例)与云南白药气雾剂对照组(72例),均于用药第5天、第10天后观察患者治疗前后的临床症状、体征的变化。结果:麝香祛痛气雾剂组:临床痊愈11.70%,显效76.10%,好转12.20%;云南白药气雾剂组:临床痊愈5.63%,显效50.70%,好转43.66%。组间比较,差异有统计学意义,麝香祛痛气雾剂组疗效明显优于云南白药气雾剂组(P<0.01);麝香祛痛气雾剂组治疗后的疼痛、压痛、肿胀、中医证候积分较云南白药气雾剂组治疗后明显下降(P<0.01),而治疗后瘀斑、功能障碍等指标积分两组比较差异无统计学意义。结论:麝香祛痛气雾剂组疗效明显优于云南白药气雾剂组,且无明显毒副作用。Objective：To evaluate the clinical efficacy and safety of Moschus analgesic aerosol（ MAA） with Yunnan Baiyao aerosol（YNBY） as control. Methods.. Adopting the randomized double blind and parallel control design, 288 patients with acute soft tissue injury （syndrome of blood stasis with qi stagnation） were randomly divided into the MAA group （216 cases） and the YNBY group （72 cases）. All patients were observed after the treatment for 5 days and 10 days. Results：In MAA group, the clinical cured rate, marked effective rate and effective rate were 11.70%, 76.10% and 12. 20%, respectively. In YNBY group, the clinical cured rate, marked effective rate and effective rate were 5.63%, 50. 70% and 43. 66%, respectively. There was statistical difference between the two groups （P〈0.01）. In MAA group, compared the YNBY group, the pain and tenderness, swelling and TCM syndrome integral decreased obviously （P〈0.01）. But there was no statistical difference of bruises, dysfunction integral between the two groups. Conclusion：Moschus analgesic aerosol is superior to Yunnan Baiyao aerosol and has no toxic and side effects.

关 键 词：麝香祛痛气雾剂 急性软组织损伤 临床疗效 

分 类 号：R685[医药卫生—骨科学]