原发性干燥综合征并发贫血28例临床研究  

Clinical analysis on 28 cases of primary sjogren's syndrome complicated with anemia

作　　者：章赛芜[1] 武洵[2] 

机构地区：[1]黄山市人民医院血液风湿科,安徽黄山245000 [2]黄山市人民医院骨科

出　　处：《临床血液学杂志》2013年第1期40-41,共2页Journal of Clinical Hematology

摘　　要：目的:观察原发性干燥综合征(pSS)并发贫血的特征。方法:回顾性分析28例pSS并发贫血患者临床资料,并对贫血的类型及与自身抗体相关性进行分析。结果:pSS并发贫血占所有住院pSS患者的44%。其中慢性病贫血(ACD)18例(64.%),缺铁性贫血(IDA)3例(10%),巨幼红细胞性贫血(MA)2例(7%),自身免疫性溶血性贫血(AIHA)3例(10%),再生障碍性贫血(AA)2例(7%)。ANA、抗SSA、SSB抗体阳性在pSS伴免疫性贫血(AIHA,AA)中更常见(P<0.05)。结论:pSS并发贫血以ACD最多见;免疫功能紊乱与贫血存在内在的关联。Objective：To observe the clinical features of primary sjogren＇s syndrome（pSS） with anemia.Method：Collect the clinical data of primary sjogren＇s syndrome with anemia from 28 patients,and analyze the types of anemia and its correlation with autoantibody in these patients.Result：28（44%） out of 64 pSS patients were primary sjogren＇s syndrome with anemia,of which 18（64%） were anemia of chronic disease（ACD）,3（10%） were iron deficiency anemia（IDA）,3（10%） were autoimmune hemolytic anemia（AIHA）,2（7%） were megaloblastic anemia（MA） and other 2（7%）cases were（aplastic anemia）AA.Patients with positive ANA,anti-SSA,anti-SSB antibody were more common in pSS with immunity anemia（AIHA,AA）,P0.05.Conclusion：ACD was the most common type of anemia in pSS complicated with anemia;There was some kind of inherent association between the disorder of immune function and anemia.

关 键 词：干燥综合征 原发性 贫血 抗体 

分 类 号：R442.8[医药卫生—诊断学]