永磁微型磁共振三维成像仪及小鼠成像  

Three-dimensional Mini-type Permanent Magnetic Resonance Imaging Device and Medical Imaging of Mice

作　　者：侯淑莲[1] 谢寰彤 侯晓吻[3] 赵强[1] 王广新[1] 陈伟[1] 张连元[1] 门秀丽[1] 孔晓燕[1] 宫凤玲[1] 

机构地区：[1]河北联合大学,唐山063000 [2]上海寰彤科教设备有限公司,上海201806 [3]杭州电子科技大学,杭州310000

出　　处：《生物医学工程学杂志》2013年第1期28-33,38,共7页Journal of Biomedical Engineering

基　　金：河北省科学技术厅立项并资助项目(08202133D);预算编号:2060402

摘　　要：为了适应磁共振成像(MRI)技术的发展和动物模型在医药研究中越来越广泛应用的新形势及高校和科研院所培养MRI人才的需要,研发制作出25mm孔径永磁微型磁共振三维成像仪。本文阐述了研发过程,着重介绍了主磁体、梯度线圈和射频线圈的设计方法,我们的独到技术及达到的性能指标。为了适应小动物个体小,需要更薄的厚度、更高的分辨率等特点,采用了三维成像技术。用自行研制的仪器进行了成像实验,得到了小鼠头部和腹部的图像,通过分析图像对仪器作了进一步的讨论。We developed a three-dimensional mini-type permanent magnetic resonance imaging （MRI） device in our lab. The purposes of this study were （1） for further development of MRI technologies, （2） for support of broade- ning practices of animal test modeling in medical research, and （3） for training more specialists from colleges or uni- versities in the field of MRI. This paper describes the research and development at our lab（s）, especially stressing on the design of the main magnet, the gradient coil and the radio frequency coil. In addition, the specific methodologies used in our lab（s） and the related data are emphasized. The 3D MR1 technologies have met the needs of using small animals, super thin sections of live animal body and high imaging resolutions. MRI images of mice head and abdomi- nal have been obtained successfully by using the imager that we developed. The imaging results and analyses have al- so been discussed.

关 键 词：永磁微型三维磁共振成像仪 主磁体 梯度线圈 射频线圈 小鼠成像 成像参数 

分 类 号：R445.2[医药卫生—影像医学与核医学]