手性磺内酰胺诱导的不对称Diels-Alder反应及其结构与手性诱导的关系  

Asymmetric Diels-Alder Reaction Induced by Chiral Sultams and the Relationship Between Structure of Sultam and Chiral Induction

作　　者：蒋腊生[1] 陈永康[2] 李慧明[2] 

机构地区：[1]中山大学化学与化学工程学院,广东广州510275 [2]香港浸会大学化学系

出　　处：《中山大学学报（自然科学版）》2000年第4期131-132,共2页Acta Scientiarum Naturalium Universitatis Sunyatseni

基　　金：香港浸会大学基金资助项目 ;香港研究资助局基金资助项目

摘　　要：Enantiomerically pure sultams (-)-2, (+)-3 and (+)-4 were synthesized.Their uses as new chiral auxiliaries in asymmetric Diels-Alder reactions with diastereoselectivity up to 99∶1 are presented. The relationship between the structure of chiral sultam and the effectiveness of asymmetric induction in Diels-Alder reactions are also discussed.Enantiomerically pure sultams (-)-2, (+)-3 and (+)-4 were synthesized.Their uses as new chiral auxiliaries in asymmetric Diels-Alder reactions with diastereoselectivity up to 99∶1 are presented. The relationship between the structure of chiral sultam and the effectiveness of asymmetric induction in Diels-Alder reactions are also discussed.

关 键 词：磺内酰胺 不对称诱导 DIELS-ALDER反应 手性诱导 

分 类 号：O623.626[理学—有机化学]