开展专项整治前后我院Ⅰ类切口手术预防用抗菌药对比分析  

Analysis to Prohylactic Use of Antibiotics for Type I Incision Operations before and after the Special Regulation of Antibiotics in our Hospital

作　　者：胡耀梅[1] 廖秋霞[1] 李昌海[1] 邵寅[1] 王玲[1] 柯清华[1] 

机构地区：[1]荆门市第一人民医院药学部,湖北荆门448000

出　　处：《药物流行病学杂志》2012年第12期606-609,共4页Chinese Journal of Pharmacoepidemiology

基　　金：湖北省荆门市科技计划项目(编号:2011S35)

摘　　要：目的:调查抗菌药专项整治对我院3种Ⅰ类切口手术(甲状腺、乳腺、腹外疝手术)预防用抗菌药的影响。方法:分别随机抽取我院2011年1～3月(对照组)和2012年1～3月(干预组)Ⅰ类切口手术病历300份,对两组预防用抗菌药情况及其合理性进行对比分析。结果:干预组抗菌药使用率由整治前的99.3%降至65.3%,首剂给药时机合理率由整治前的18.8%升至89.3%,差异均有统计学意义(P<0.05);抗菌药种类选择合理性提高,给药时间缩短、联合用药、无依据更换药物等方面明显改善。整治前后切口感染率分别为1.3%、1.0%,差异无统计学意义(P>0.05)。结论:开展专项整治后,我院3种Ⅰ类切口手术预防用抗菌药的合理性明显改善,应继续深化抗菌药专项整治,促进抗菌药规范使用。To investigate the antibiotics prophylaxis in three kinds of type I incision operations （ thy- roid surgery, breast surgery and abdominal external hernia surgery） in our hospital through the special regulation of the use of antibiotics. Methods ：300 cases with type I incision operation were selected as the controlled group during Jan. and Mar. 2011 and the other 300 cases, as the intervention group during Jan. and Mar. 2012 and contrastive rationality of antibiotics usage was analyzed. Results：After the intervention, the usage rate of antibiotics decreased from 99.3% to 65.3% （P 〈 0.05 ）, the rational rate of medication time increased from 18.8% to 89.3% （P 〈0.05 ）, the rationality of drug selection was obviously improved and medication time was significantly shorter. Irrational drug combination and drug replacement were obviously improved. The wound infection rate in the control＇ s was 1.3% and the rate in the intervention＇ s was 1.0% （ P 〉 0.05 ）. Conclusion ： After intervention, various indexes about type I incision operations were significantly improved. So the special reulation of antibiotics must be constantly deepened to promote the rational use of antibiotics.

关 键 词：抗菌药专项整治 I类切口手术 抗菌药 

分 类 号：R978.1[医药卫生—药品]