西安地区健康成人幽门螺杆菌感染状况调查和相关因素分析  

Analysis Investigation on Infection Status and the Related Factors of Itelicobacter Pylori in Health Adult Group in Xi~ an Area

作　　者：刘杨[1] 王菁[1] 邢瑞青[1] 郑善銮[1] 张小宁[1] 程晓东[1] 彭道荣[1] 

机构地区：[1]第四军医大学西京医院全军检验医学研究所,西安710032

出　　处：《现代检验医学杂志》2012年第6期79-82,85,共5页Journal of Modern Laboratory Medicine

摘　　要：目的了解西安地区健康成人幽门螺杆菌（H．pylori）感染状况，为制定有效的防治措施提供依据。方法对13632例健康成人进行HP—IgG抗体和血细胞的检测，并对检测结果进行统计分析。结果①西安地区健康成人H．pylori感染率为40．562％，其中男性H．pylori感染率为40．39％，女性H．pylori感染率为40．77％，男性和女性感染率差异无统计学显著性意义（P〉0．05）；②不同年龄及性别健康人群H．pylori感染率呈上升趋势。各年龄组与20～29岁年龄组比较，Hp—IgG抗体检出率差异非常显著（P〈O．01），不同性别间只有40~49年龄组和50～59年龄纽比较差异具有统计学意义（P〈0．05）；③不同季节H．pylori感染率不同，春季与夏季感染率分别为36．54％和36．74％，低于秋冬季节（44．43％和44．05％），两者比较差异非常显著（P〈O．01），春季与夏季感染率及秋季与冬季感染率比较则差异无统计学意义（P〉0．05）；④Hp-IgG阳性组白细胞计数[（6．05±1．59）×10。／L]明显高于Hp—IgG阴性组[（5．73±1．58）×lO。／L3（P〈0．05）。⑤经济收入低、家庭人口数多及人均居住面积小，则H．pylori感染率高，两者比较差异显著（P〈O．05），喜食水果及食醋者H．pylori感染率低，两者比较差异具有统计学显著性意义（P〈O．05）。结论西安地区健康成人H.pylori感染率为40．52％，低于全国平均水平，随年龄增加有增高趋势。秋冬季节H．pylori感染率高；经济生活条件，饮食卫生习惯等是H．pylori感染的重要危险因素。防治H．pylori感染具有重要意义。Objective To investigate the infection of H. pylori in health adult in Xi＇an,area in oder to provide valid evidence for the control. Methods 13 632 health adults were selected. The serm IgG antibodies to H. pylori and whole blood hemo- cyte which were analysed by statistics were measured. Results ①The positive rate of H. pylori IgG in health adults in Xi＇ an was 40.52% （mail 40. 39 % and femail 40. 77%） ,hut there was no statistical significance between mail and femail （P〉0. 05）. ②The positive rate of H. pylori IgG increased with age and gender. Compared to the 20～29 group,the positive rate of H. pylori IgG in other age groups had significant difference （P〈0.01） while only 40～49 group and 50～59 group showed obvious statistical significance between different genders （P〈0.05）. ③The positive rate of H. pylori IgG in spring and summer （36.54 % and 36.74%） was lower significancetly than that in autumn and winter （44.43 % and 44.05 % ）（P〈 0.01）. But there was no statistical significance between winter group and other three seasons （P〉0.05）. ④The WBC of positive group[（6.05±1.59） × 109/L]was higher significantly than that of negative group[（5.73 ±1.58） × 109/L] （P〈 0.05）. ⑤Compared to the respecti＇ge other group,the positive rate of H. pylori IgG was higher in the groups of large fami- lies, low income, small per capita living area, but lower in the groups of being fond of eating fruits and vinegar. These differ- ences had statistical significance （P〈0.05）. Conclusion The positive rate of H. pylori IgG （40.52%） in health adult in Xi＇an area which was lower than the average level in china showed a general shift towards higher with the increase of age. The infection of H. pylori was higher in autumn and winter. Economics and life condition,dietary health habit and education level were the risk factors for H. pylori infection. Taking measures to prevent H. pylori infection might have important sig- nificance.

关 键 词：西安地区 幽门螺杆菌 健康成人 感染率 流行病学 

分 类 号：R378[医药卫生—病原生物学] R181.32[医药卫生—基础医学]