盐酸戊乙奎醚与丙泊酚联合用于无痛人工流产术的临床研究  

Effect of Penehyclidine Hydrochloride with Propofol Analgesia on the Postoperative Pain in Painless Artificial Abortion

作　　者：夏明[1] 姚蓓[1] 刘梦婷[1] 童建华[1] 刘杨[1] 李伟彦[1] 

机构地区：[1]南京军区南京总医院麻醉科,江苏南京210002

出　　处：《现代生物医学进展》2012年第34期6677-6680,共4页Progress in Modern Biomedicine

基　　金：国家自然科学基金项目(30872424)

摘　　要：目的:评价盐酸戊乙奎醚联合丙泊酚减轻人工流产术后疼痛的效果。方法:ASAI-II级人工流产术患者100例,随机分为观察组和对照组。处理组先缓慢静脉注射盐酸戊乙奎醚注射剂1mg,30min后静脉注射丙泊酚2.5mg/kg;;对照组单独静脉注射丙泊酚2.5mg/kg。两组丙泊酚静注速率均为5mg/s。结果:处理组苏醒即刻苏醒后15min和30min宫缩痛的VAS评分分别为(3.13±0.15)、(2.02±0.11)和(0.87±0.09)分,明显低于对照组的(4.47±0.35)、(3.54±0.14)及(2.01±0.12)(P<0.01)。结论:盐酸戊乙奎醚联合丙泊酚镇痛能减轻人工流产术后的疼痛。Objective： To evaluate the effect of Penehyclidine Hydrochloride with propofol analgesia on the postoperative pain in painless artificial abortion.Methods： One hundred ASA I-II patients undergoing artificial abortion were randomly assigned to two groups（n=50 each）： control group（con） were was administrated propofol 2.5mg/kg alone.Treatment group was administrated intravenously Penehyclidine Hydrochloride 1mg followed by propofol 2.5mg/kg 30minutes later.The speed of intravenously injection of propofol was 5mg/s in two groups.Results： The VAS scores at immediate time of awaked from anesthesia,15min and 30min after that were（3.13± 0.15）、（2.02±0.11）and（0.87±0.09）,respectively,in treatment group,which were significantly shorter than（4.47±0.35）、（2.02± 0.11）and（2.01±0.12）in control grouo（P0.01）.Conclusion： Penehyclidine Hydrochloride combined with propofol anesthesia can effectively relieve the postoperative pain of artificial abortion.

关 键 词：盐酸戊乙奎醚 丙泊酚 人工流产术 术后疼痛 

分 类 号：R714.21[医药卫生—妇产科学] R614[医药卫生—临床医学]