重型颅脑损伤进展性脑内血肿的相关危险因素分析  

Risk factors of progressive intracerebral hematoma in severe traumatic brain injury

作　　者：李立国[1] 赵强[1] 

机构地区：[1]宁波开发区中心医院神经外科,315800

出　　处：《中国医师进修杂志》2013年第2期12-14,共3页Chinese Journal of Postgraduates of Medicine

摘　　要：目的探讨重型颅脑损伤进展性脑内血肿（PIH）的相关危险因素，为颅脑损伤的诊断和治疗提供理论参考。方法回顾性分析2008年3月至2012年3月收治的96例重型颅脑损伤患者的临床资料，对PIH的相关危险因素进行单因素分析和多因素Logistic回归分析，筛选PIH的相关危险因素。结果36例患者发生PIH，发生率为37．5％（36／96）。单因素分析显示：年龄、入院时格拉斯哥昏迷量表（GCS）评分、受伤至首次颅脑CT检查时间、脑挫伤、蛛网膜下隙出血、硬脑膜外血肿、硬脑膜下血肿与PIH发生有关（P〈0．01或〈0．05）。多因素Logistic回归分析表明：年龄、脑挫伤、蛛网膜下隙出血、硬脑膜外血肿、硬脑膜下血肿是PIH发生的危险因素（P〈0．05或〈0．01）。结论充分认识PIH发生的相关危险因素，并给予及时的干预措施是降低重型颅脑损伤患者致残率和病死率的关键。Objective To investigate the risk factors of progressive intracerebral hematoma （PIH） in severe traumatic brain injury （STBI） and provide reference for diagnosis and treatment of STBI. Methods The clinical information of 96 patients of STBI from March 2008 to March 2012 were retrospectively analyzed, the risk factors of PIH were analyzed by the univariate and multivariate Logistic regression analysis. Results Thirty-six patients occurred PIH, the incidence rate of PIH was 37.5% （36/96）. The univariate regression analysis showed that the age, admission GCS scores, injury to the first CT time, brain contusion, subaraehnoid hemorrhage, epidural hematoma, subdural hematoma had certain relation with PIH （P 〈 0.01 or 〈 0.05）. Multivariate Logistic regression analysis showed that the age, brain contusion, subarachnoid hemorrhage, epidural hematoma, subdural hematoma were risk factors of PIH （P 〈 0.05 or 〈 0.01 ）. Conclusion Fully aware of the risk factors of PIH and timely intervention is the key to reduce the morbidity and mortality of STBI.

关 键 词：颅脑损伤 颅内出血 危险因素 

分 类 号：R651.15[医药卫生—外科学]