超声乳化手术治疗葡萄膜炎并发白内障的疗效及对血-房水屏障功能的影响  

Clinical efficacy of phacoemulsificatioll in treatment of uveitis combined with cataract and the influence on blood-aqueous barrier

作　　者：孙昊[1] 

机构地区：[1]淮安市第二人民医院眼科,江苏淮安223001

出　　处：《中华医院感染学杂志》2013年第3期573-574,共2页Chinese Journal of Nosocomiology

摘　　要：目的探讨超声乳化手术治疗葡萄膜炎并发白内障的临床疗效及其对血-房水屏障功能的影响研究。方法选择医院2008年2月-2011年2月收治的100例葡萄膜炎并发白内障患者,分为对照组与治疗组,每组各50例;治疗组给予超声乳化手术治疗,对照组给予常规治疗方法,观察两组患者的治疗效果,测定两组患者治疗前后的视力及房水蛋白浓度。结果治疗后,治疗组患者术后1、7、30、90d最佳矫正视力>0.5的眼数比例分别为76.0%、90.0%、92.0%、98.0%均明显高于对照组,差异有统计学意义(P<0.05);治疗组患者的房水蛋白浓度水平(7.88±0.05)均明显高于对照组的(9.66±0.01),差异有统计学意义(P<0.05);两组患者均未出现不良反应。结论超声乳化手术治疗可有效治疗葡萄膜炎并发白内障,不良反应小,值得推广应用。OBJECTIVE To investigate the clinical efficacy of phacoemulsificatioll in the treatment of uveitis combined with cataract and its influence on the blood-aqueous barrier.METHODS A total of 100 children with the uveitis combined with cataract were selected from Feb 2008 to Feb 2011,and they were divided into the control group and the treatment group,with 50 cases.The control group was given the conventional treatment while the treatment group was given the phacoemulsificatioll.The clinical efficacy,the vision and the aqueous protein concentration were compared between the two groups.RESULTS After the treatment,the proportion of the eyes with best corrected visual acuity more than 0.5 were 76.0%,90.0%,92.0% and 98.0% respectively on the first,seventh,thirtieth,and ninetieth day after the surgery,which were significantly higher than that of the control group,the differences were statistically significant（P0.05）.The aqueous protein concentration was significantly higher in the treatment group（7.88±0.05） than in the control group（9.66±0.01）,the difference was statistically significant（P0.05）.No adverse reactions occurred in both groups of the patients.CONCLUSION Phacoemulsificatioll,with less adverse reactions,can effectively treat the uveitis combined with cataract,which is worthy of the clinical promotion.

关 键 词：超声乳化手术 葡萄膜炎 白内障 血-房水屏障功能 

分 类 号：R181.32[医药卫生—流行病学]