true-FISP心脏MRI评价猪右心室容积可重复性与准确性的初步研究  

Primary research of repeatability and accuracy of breath-freetrue-FISP cine magnetic resonance imaging in evaluating pig right ventricular volume

作　　者：刘慧慧[1] 许云飞[1] 戴学标[1] 朱彦[1] 刘文[1] 

机构地区：[1]江苏大学附属医院影像科,江苏镇江212001

出　　处：《现代医药卫生》2013年第2期189-190,共2页Journal of Modern Medicine & Health

摘　　要：目的用真实稳态进动快速成像序列（true-FISP）心脏磁共振成像（MRI）方法测量猪右心室容积并评价其测量的可重复性与准确性。方法选择26只健康实验猪,用常规T1WI序列及true-FISP心脏MRI方法获得覆盖右心室的短轴像;由2名高年资观察者分别进行2次独立测定2个序列所有入选者的心室容积,包括测量舒张末期容积（EDV）及收缩末期容积（ESV）,评价右心室容积在观察者内部及观察者间的可重复性及准确性。结果常规T1WI序列及true-FISP观察者间可重复性误差分别为：EDV 9.82%、4.88%,ESV 9.45%、3.94%;高年资观察者内部可重复性误差分别为：EDV 1.29%、0.77%,ESV 1.44%、0.89%;个体内部可重复性误差范围分别为：EDV 0.52%~1.61%、0.14%~1.11%,ESV 0.55%~1.70%、0.17%~1.14%。常规T1WI序列各项可重复性误差均高于true-FISP（P〈0.05）。以常规T1WI序列为对照,true-FISP序列测量右心室容积的系统误差分别为：EDV（-3.80±3.93）%,ESV（-3.77±3.87）%,随机配对误差分别为：EDV（4.68±2.70）%,ESV（4.55±2.64）%。2种方法比较,差异无统计学意义（t=0.92,P=0.36）。结论 true-FISP心脏MRI方法检测右心室容积具有较好可重复性及准确性。Objective To evaluate the accuracy and reproducibility of pig right ventricular（RV）volume measured with breath-freetrue-FISP cine magnetic resonance imaging（MRI）.Methods 26 healthy pigs were enrolled in the study group.T1WI and true-FISP cine imaging with multiple breath held were performed in short axis imaging sections to encompass the entire ventricles.Two senior doctors measured the volume including EDV and ESV twice separately and evaluated the repeatability and accuracy on right ventricular volume in intra-observer and inter-observer.Results The inter-observer repeatability error was EDV 9.82%,4.88% and ESV 9.45%,3.94% in T1WI and true-FISP;the intra-observer repeatability error of senior docters was EDV 1.29%,0.77% and ESV1.44%,0.89%;the inter individual repeatability range was EDV 0.52%-1.61%,0.14%-1.11% and ESV 0.55%-1.70%,0.17%-1.14%.The repeatability error of true-FISP segmentaion was proved to be significantly smaller than T1WI（P0.05）.The systemic difference between results obtained with true-FISP measurement was EDV（-3.80±3.93）% and ESV（-3.77±3.87）%,and random matching error was EDV（4.68±2.70）% and ESV（4.55±2.64）%.There was no statistical difference between the volume results measured by two methods（t=0.92,P=0.36）.Conclusion The assessment of RV volume by breath-freetrue-FISP has a better accuracy and reproducibility.

关 键 词：磁共振成像 心室 放射摄影术 心室功能 右 猪 

分 类 号：R445.2[医药卫生—影像医学与核医学]