化学发光免疫分析与酶联免疫吸附试验检测乙型肝炎病毒标志物比较分析  

Comparative analysis of CLIA and ELISA for detecting HBV-markers

作　　者：司志霖 蔡晓宁[1] 

机构地区：[1]遂宁市第一人民医院检验科,四川遂宁629000

出　　处：《现代医药卫生》2013年第2期196-196,198,共2页Journal of Modern Medicine & Health

摘　　要：目的比较化学发光免疫分析(CLIA)与酶联免疫吸附试验(ELISA)两种方法检测乙型肝炎病毒标志物(HBV-M)的临床价值。方法分别用CLIA和ELISA对210份血清标本进行HBV-M平行检测,然后对两种方法检测结果进行比较分析。结果 CLIA和ELISA检测血清HBV-M结果比较,差异无统计学意义(P>0.05)。结论两种方法检测HBV-M结果具有高度一致性,但是CLIA检测HBV-M较ELISA法准确、灵敏。Objective To compare the clinical value of the enzyme-linked immunosorbent assay（ELISA） and the chemiluminescence immunoassay（CLIA）for detecting hepatitis B vivus（HBV）markers.Methods 210 serum samples were parallellydetected by CLIA and ELISA respectively and the detection results were comparatively analyzed.Results No statistical difference between the results of CLIA and ELISA were found（P0.05）.Conclusion The 2 methods of CLIA and ELISA have the high consistency in the detection results of HBV markers,but CLIA is more accurate and more sensitive than ELISA.

关 键 词：肝炎表面抗原 乙型 肝炎e抗原 乙型 肝炎抗体 乙型 化学发光法 免疫测定 酶联免疫吸附测定 对比研究 

分 类 号：R512.62[医药卫生—内科学]