冠状动脉介入治疗应用国产药物洗脱支架术后近期疗效观察  

Efficacy of domestic drug-eluting stent implantation in treatment of coronary intervention

作　　者：梁莉[1] 

机构地区：[1]湖南省常德市第一人民医院,湖南常德415900

出　　处：《中国当代医药》2013年第5期35-36,共2页China Modern Medicine

摘　　要：目的对比国产雷帕霉素药物洗脱支架(Firebird)与进口雷帕霉索药物洗脱支架(Cypher)的安全性及近期疗效。方法选择本院2009年10月～2011年12月收治的急性心肌梗死患者140例,分为国产组70例和进口组70例,均在冠状动脉造影后,行经皮冠状动脉介入置入支架治疗,术后随访1年,对比两组近期疗效。结果两组患者均无再发心肌梗死及不良心血管事件发生。两组各发生1例支架内再狭窄,发生率均为1.4%,组间差异无统计学意义(P>0.05);国产组与进口组支架内缺血性胸痛发作例数分别为1、2例,两组差异无统计学意义(P>0.05)。结论国产与进口药物洗脱支架在急性心肌梗死的择期介入治疗中的近期应用效果相似,值得推广。Objective To compare security and short-term effect of domestic rapamycin drug-eluting stent （Firebird） and imported rapamycin cable drug - eluting stent （Cypher）. Methods One hundred and forty patients with acute myocar- dial infarction from October 2009 to December 2011 were randomly divided into domestic group of 70 patients and import group of 70 patients, all patients were given coronary angiography, and then given percutaneous coronary inter- vention treatment, then all patients were followed up for one year, the short-term effect between the two groups was compared. Results Two groups of patients had no recurrence of myocardial infarction and adverse cardiovascular events. The two groups each had one case of stent restenosis, the incidence was both 1.4%, the difference between the two groups was not statistically significant （P 〉 0.05）; ischemic chest pain episodes number of patients in domestic group and imported group were 1 and 2 cases, the difference between the two groups was not statistically significant （P 〉 0.05）. Conclusion Short-term effect of domestic and imported drug-eluting stent in percutaneous coronary intervention is similar, and it is worthy of promotion.

关 键 词：急性心肌梗死 冠状动脉介入治疗 国产 进口 药物洗脱支架 近期疗效 

分 类 号：R54[医药卫生—心血管疾病]