糖尿病及其并发症中microRNAs的作用  

Role of microRNAs in diabetes and its complications

作　　者：朱柄铭[1] 温旺荣[1] 

机构地区：[1]暨南大学附属第一医院临床医学检验中心,广东广州510630

出　　处：《分子诊断与治疗杂志》2013年第1期61-66,共6页Journal of Molecular Diagnostics and Therapy

摘　　要：糖尿病及其并发症严重威胁着人类健康,它们的发生可能涉及到多重复杂因素,然而,具体的发病机制尚不明确。MicroRNAs(miRNAs)是一系列全新的非编码小分子RNAs,其参与人体许多生理和病理过程的调控。新近研究发现,miRNAs在糖尿病及其相关并发症的发病机制中起着重要作用,这些相关miRNAs也为糖尿病的诊断和治疗提供了一个全新视角。Diabetes and its complications are a serious threat to human health, which occurrence may be caused by multiple and complex factors, however, their specific pathogenesis is not clear. MicroRNAs （miRNAs） are a novel series of non-coding small RNAs that have been involved in a variety of the body＇s physiological and pathological processes. Recent research has suggested that miRNAs plays a critical role in the pathogenesis of diabetes and its related complications. These related miRNAs provide a brand new perspective for diagnosis and treatment of diabetes.

关 键 词：糖尿病 MIRNA 糖尿病并发症 诊断与治疗 

分 类 号：R587.1[医药卫生—内分泌]