临床药师干预对呼吸病区抗菌药物应用的影响  

Effect of clinical pharmacist intervention on the application of antimicrobial agents in respiratory ward

作　　者：顾建英 顾萍 

机构地区：[1]上海市浦东新区南华医院药剂科,上海201300

出　　处：《上海医药》2013年第3期39-42,共4页Shanghai Medical & Pharmaceutical Journal

摘　　要：目的:观察临床药师干预对呼吸病区抗菌药物应用的影响。方法:分别选取呼吸病区2011年1-5月(干预前)和2012年1-5月(干预后)的抗菌药物使用数据,比较抗菌药物合理使用情况,计量资料采用t检验,计数资料采用x2检验。结果:干预后该病区抗菌药物使用率由96.08%降至71.43%;单药应用率由19.18%上升为41.76%(P<0.01),二联用药由78.78%降至56.47%(P<0.01);不合理用药的表现由55.69%降至13.44%(P<0.01)。结论:临床药师的干预能促进抗菌药物的合理应用。Objective： To observe the effect of clinical pharmacist interventions on the application of antimicrobial agents in respiratory ward. Methods： Data of antimicrobial medication in January-May 2011 （before intervention） and in January-May 2012 （intervention） in our respiratory ward were selected to compare the rational use of antimicrobials in case, and measurement and count data were checked by t test and xe test, respectively. Results： After the intervention, the rate of the use of antimicrobial agents was reduced from 96.08% to 71.43% in this ward. Single drug application rate increased from 19.18% to 41.76% （P 〈 0.01） and the combined medication of two drugs decreased from 78.78% to 56.47% （P 〈 0.01）. Irrational drug use decreased from 55.69% to 13.44% （P 〈 0.01）. Conclusion： The rational use of antimicrobials can be promoted by the intervention of clinical pharmacists.

关 键 词：临床药师 抗菌药物 干预 合理用药 

分 类 号：R56[医药卫生—呼吸系统]