2型糖尿病患者急性心肌梗死急性期血脂特点  

The characteristics of blood fat in type 2 diabetes patients in early phase of acute myocardial infarction

作　　者：李艳艳[1] 冯津萍[2] 陈刚[2] 路雅茹[2] 寇璐[2] 李杨[2] 

机构地区：[1]天津医科大学研究生院,天津300070 [2]天津市胸科医院心内科,天津300051

出　　处：《天津医科大学学报》2013年第1期67-69,共3页Journal of Tianjin Medical University

摘　　要：目的:分析急性心肌梗死(AMI)合并2型糖尿病患者在AMI急性期血脂水平变化特点。方法:连续入选876例因AMI住院的患者,入院后24 h内抽取空腹肘静脉血,检测血脂水平。根据患者是否合并2型糖尿病分为AMI非糖尿病组(n=557)及AMI糖尿病组(n=319),比较两组患者血脂水平差异。结果:于AMI急性期,AMI糖尿病组总胆固醇(CHO)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDLC)、载脂蛋白B(apoB)均高于AMI非糖尿病组,其中CHO、TG、LDLC差异有统计学意义(P<0.05),而高密度脂蛋白胆固醇(HDLC)、载脂蛋白A(apoA)低于AMI非糖尿病组,其中HDLC差异有统计学意义(P<0.05)。结论:AMI合并2型糖尿病患者在AMI急性期血脂水平明显异常,提示应加强冠心病合并2型糖尿病患者血脂异常的防治。Objective： To analyze the characteristics of blood fat level in type 2 diabetes patients in early phase of acute myocardial in- faretion（AMI）. Methods： The hospitalized AMI patients（n=876） were chosen and their blood fat level was detected within 24 hours after hospitalization. All patients were divided into the non-diabetic AMI group（n=557） and diabetic AMI group （n=319） according to whether the AMI patients had complicated type 2 diabetes. The level of blood fat was compared between the two groups. Results： The level of total cholesterol （CHO）, triglycerides （TG）, low density lipoprotein cholesterol （LDLC）, apolipoprotein B （apoB） were higher in patients with type 2 diabetes than those in patients without type 2 diabetes, among which CHO, TG, LDLC differences were statistically significant （P 〈 0.05）, the level of high-density lipoprotein cholesterol （HDLC）, apolipoprotein A （apoA） were lower in patients with type 2 diabetes than those in patients without type 2 diabetes, among which HDLC difference was statistically significant （P 〈 0.05）. Conclusion ： The level of blood fat in type 2 diabetes patients in early phase of AMI are apparently unusual, It should be strengthen the prevention and control of dyslipidemia of the CHD patients who with type 2 diabetes.

关 键 词：急性心肌梗死 2型糖尿病 血脂 

分 类 号：R587.2[医药卫生—内分泌]