球后注射联合云克治疗Graves眼病的疗效观察及护理  

THERAPEUTIC EVALUATION AND NURSING CARE OF RETROBULBAR INJECTION COMBINE WITH INTRAVENOUS INJECTION OF MDP FOR OPHTHALMIC GRAVES′ DISEASE

作　　者：吴继珍[1] 范义湘[1] 梁智欣[1] 黄凯龄[1] 李科斌[1] 

机构地区：[1]广东省第二人民医院核医学科,广东广州510317

出　　处：《现代医院》2013年第1期69-70,共2页Modern Hospitals

基　　金：广东省医学科研基金(编号:A2009135)

摘　　要：目的探讨33例球后注射联合静脉注射云克治疗Graves眼病的疗效观察及护理。方法用甲泼尼龙琥珀酸钠20 mg+维生素B120.5ug球后注射,联合静脉注射云克11 mg(鍀[99TC]亚甲基二膦酸盐注射液),每日1次,5次为1个疗程,注射1个疗程休息2周,连续注射5个疗程,3个月后随访观察记录自觉症状、眼征情况。结果 33例(59眼)患者接受治疗,显效率30.51%(18/59),有效率62.71%(37/59),无效率6.78%(4/59),总有效率93.22%;大部分患者畏光、流泪、眼胀眼痛等症状及充血水肿、眼睑浮肿等体征得到明显改善或消失。结论球后注射联合静脉注射云克治疗甲状腺相关眼病效果显著,不良反应小,安全性高。Objective To investigate therapeutic evaluation and nursing care to 33 cases （59 eyes） of Oph- thalmic Graves＇ disease patients which received retrobulbar injection combine with intravenous injection of MDP. Methods Retrobulbar injection with methylpre dnisolone sodium succinate （ methylpre - dnisolone sodium succinate 20 mg＋ Vitamin B12 O. 5 ixg） combine with intra - venous injection of MDP（ Technetium [ 99TC ] methylene diphos- phonate injection, llmg）, one time per day, 5 times for a course of treatment. Rest for two weeks after each course, continuous injection for 5 courses. To follow - up the obsetv - ation to symptoms and eye situation of patients after 3 months. Results 33 patients（59 eyes） received the treatment, significant effect rate 30. 51% （18/59）,effect rate 62. 71% （37/59）, in effect rate 6.78（4/59） ,total effect rate 93.22% ; The symptoms of phtophobia, watery eyes, eye pain and the sign of swelling, edema with eyelid in most patients had significant improve or disappear. Conclu- sion Effect of treatment with retrobulbar injection combine with intravenous injection of MDP to Ophthalmic Graves＇ disease was significant, adverse reations and safty.

关 键 词：GRAVES眼病 球后注射 云克 护理 

分 类 号：R581.1[医药卫生—内分泌]