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机构地区:[1]北京市怀柔区渤海镇卫生院,北京101405 [2]吉林省中医药科学院肝病科,吉林长春130021
出 处:《中国医药导报》2013年第6期4-6,共3页China Medical Herald
基 金:吉林省中医药管理局中医药科技项目(编号2011-js22)
摘 要:目的探讨塌渍照射法对肝硬化腹水患者血清腹水白蛋白梯度(SAAG)、血小板参数及红细胞参数的影响。方法选取2011年10月~2012年5月60例肝硬化腹水患者为研究对象,将其随机分为对照组(常规治疗组)和观察组(塌渍照射法组),每组各30例;对照组给予常规治疗,观察组在常规治疗基础上给予塌渍照射法治疗,对两组患者治疗前及治疗后5、10、20 d的SAAG、血小板参数及红细胞参数水平进行比较。结果治疗后5、10、20 d观察组SAAG值和≥11 g/L者比例均低于对照组,差异均有统计学意义(均P<0.05);治疗后5、10、20 d观察组血小板计数(PLT)、血小板压积(PCT)、平均血小板体积(MPV)及血小板分布宽度(PDW)均高于对照组,差异均有统计学意义(均P<0.05);治疗后5、10、20 d观察组平均红细胞血红蛋白(MCH)、平均红细胞血红蛋白浓度(MCHC)、红细胞体积分布宽度(RDW)及平均红细胞容积(MCV)均低于对照组,血细胞比容(HCT)高于对照组,差异均有统计学意义(均P<0.05)。结论塌渍照射法在改善肝硬化腹水患者SAAG、血小板参数及红细胞参数方面的效果较佳,对于改善患者的疾病状态发挥着积极的临床作用。Objective To investigate the influence of Tazi and irradiation method for the serum aseites albumin gradi- ent (SAAG) platelet parameters and erythrocyte parameters of patients with cirrhosis ascites. Methods 60 patients with cirrhosis ascites from October 2011 to May 2012 were selected as research objects, all the patients were randomly di- vided into control group and observation group with 30 cages in each group; patients in control group were treated with routine treatments,patients in observation group were treated with routine treatment combined with Tazi and irradiation method. The SAAG, platelet parameters and erythrocyte parameters of two groups before and 5, 10 and 20 days after the treatment were compared. Results The SAAG level and its≥ 11 g/L rate of observation group 5, 10 and 20 days after the treatment were all lower than those of control group, ihe difference were statistically significant (P 〈 0.05); PLT, PCT, MPV and PDW of observation group 5, 10 and 20 days after the treatment were all higher than those of control group, the difference were statistically significant (P 〈 0.05); MCH, MCHC, RDW and MCV of observation group 5, 10 and 20 days after the treatment were all lower than those of control group, MCV of observation group 5, 10 and 20 days after the treatment was higher than those of control group, the differences were statistically significant (P 〈 0.05). Conclusion The effect of Tazi and irradiation method in improving the SAAG, platelet parameters and ery- throcyte parameters of patients with cirrhosis ascites is good, and it plays an active clinical role in improving the disease state of patients.
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