翻白草中酚酸类化学成分的研究  

Study on the chemical constituents of phenolic acids from Potentilla discolor

作　　者：肖草茂[1] 李玉云[1] 胡蓉[1] 曾宪仪[1] 肖小华[1] 王丽华[1] 朱才庆[1] 

机构地区：[1]江西省药物研究所,江西南昌330029

出　　处：《华西药学杂志》2013年第1期10-12,共3页West China Journal of Pharmaceutical Sciences

基　　金：江西省主要学科学术和技术带头人培养计划资助项目(编号:2010DR01700)

摘　　要：目的研究翻白草中的酚酸类化学成分。方法采用硅胶、大孔树脂及聚酰胺柱色谱等手段,分离纯化翻白草中70%乙醇提取部位的酚酸类成分,并通过光谱法鉴定结构。结果分离并鉴定了6个单体化合物,分别为3-甲基鞣花酸-4'-O-α-L-鼠李糖苷(I)、3,3',4-三甲基鞣花酸-4'-O-β-D-葡萄糖苷(Ⅱ)、3,3'-二甲基鞣花酸(Ⅲ)、没食子酸(Ⅳ)、委陵菜酸(Ⅴ)、山奈酚-3-O-β-D-6-O-(对羟基桂皮酰基)-吡喃葡萄糖苷(Ⅵ)。结论化合物Ⅱ、Ⅲ、Ⅴ、Ⅵ为首次从该植物中分离得到。OBJECTIVE To study the phenolic acids constituents in Potentilla discolor.METHODS The compounds were isolated by silica gel chromatography,macroporous resins and polyamide column chromatography from the 70% ethanol extract,and their structures were identified by spectroscopy.RESULTS Six compounds were isolated from Potentilla discolor and their structures were identified as 3-methylellagic acid-4′-O-α-L-rhamnopyranoside（I）,3,3′,4-trimethylellagic acid-4′-O-β-D-glucopyranoside（Ⅱ）,3,3′-dimethylellagic acid（Ⅲ）,gallic acid（Ⅳ）,tormentic acid（Ⅴ）and kaempferol-3-O-β-D-6-O-（p-hydroxycinnamoyl）-gluco pyranoside（VI）.CONCLUSION The Compounds Ⅱ,Ⅲ,Ⅴ,Ⅵ were isolated from this herb for the first time.

关 键 词：翻白草 酚酸类成分 3-甲基鞣花酸-4'-O-α-L-鼠李糖苷 3 3' 4-三甲基鞣花酸-4'-O-β-D-葡萄糖苷 3 3'-二甲基鞣花酸 

分 类 号：R284[医药卫生—中药学]