多指标正交法优选盐制补骨脂饮片的炮制工艺  

Optimization of preparation of salt-processed Psoraleae Fructus medicines with multi-index orthogonal method

作　　者：殷放宙[1] 李林[1] 李伟东[1] 陆兔林[1] 蔡宝昌[1] 

机构地区：[1]南京中医药大学药学院,江苏南京210046

出　　处：《中国中药杂志》2013年第3期346-349,共4页China Journal of Chinese Materia Medica

基　　金：国家自然科学基金项目(30701108);江苏高校优势学科建设工程项目PAPD(ysxk-2010);南京中医药大学中药学一级学科开放课题项目(2011ZYX2-008)

摘　　要：目的:采用正交试验法优选盐制补骨脂工艺。方法:以其所含的香豆素、黄酮、酚类等12个成分为考察指标,采用L9(34)正交试验比较不同因素对盐制补骨脂的影响。结果:确定的最佳工艺为100 g补骨脂加2 g盐,闷润2 h,150℃炒制10 min。结论:正交试验的结果合理、可靠,为盐制补骨脂的炮制工艺提供了依据。Objective： To optimize the preparation of salt-processed Psoraleae Fructus by the orthogonal test method. Method： With the 12 components such as eoumarin, flavone and phenolics as study indexes, a L9 （34） orthogonal test was adopted to compare the effect of different factors on salt-processed Psoraleae Fructus. Result： According to the finalized optimal process, 100 g Psoraleae Fructus was added with 2 g salt, moistened for 2 hours, and then fried for 10 min at 150% Conclusion： The orthogonal test is so rea- sonable and reliable that it can provide basis for the preparation of salt-processed Psoraleae Fructus.

关 键 词：补骨脂 盐制 正交试验 

分 类 号：R283[医药卫生—中药学]