Anti-diabetic Effects of Polysaccharides from Ethanol-insoluble Residue of Schisandra chinensis（Turcz.） Baill on Alloxan-induced Diabetic Mice  

作　　者：ZHAO Ting MAO Guang-hua ZHANG Mini LI Fang ZOU Ye ZHOU Ye ZHENG Wei ZHENG Da-heng YANG Liu-qing WUXiang-yang 

机构地区：[1]College of Food and Biological Engineering [2]College of Chemistry and Chemical Engineering, [3]College of Pharmacy, [4]College of Environment, Jiangsu University, Zhenjiang 212013, P. R. China

出　　处：《Chemical Research in Chinese Universities》2013年第1期99-102,共4页高等学校化学研究（英文版）

摘　　要：The ethanol-insoluble residue of Schisandra generated during lignans industrial production is usually treated as solid waste. However, there is active polysaccharide which could be used in it. In this work, the water-soluble polysaccharides from the ethanol-insoluble residue of Schisandra（ESCP） were obtained and their anti-diabetic effect was evaluated. The results indicate that ESCP could significantly reduce the blood glucose level in alloxan-induced diabetic mice. Moreover, the ESCP could significantly improve the lipid metabolism and increase the content of liver glycogen in alloxan-induced diabetic mice. The results indicate that ESCP could be developed into a potential natural hypoglycemic agent.The ethanol-insoluble residue of Schisandra generated during lignans industrial production is usually treated as solid waste. However, there is active polysaccharide which could be used in it. In this work, the water-soluble polysaccharides from the ethanol-insoluble residue of Schisandra（ESCP） were obtained and their anti-diabetic effect was evaluated. The results indicate that ESCP could significantly reduce the blood glucose level in alloxan-induced diabetic mice. Moreover, the ESCP could significantly improve the lipid metabolism and increase the content of liver glycogen in alloxan-induced diabetic mice. The results indicate that ESCP could be developed into a potential natural hypoglycemic agent.

关 键 词：Schisandra chinensis（Turcz.） Baill Ethanol-insoluble residue Polysaccharide Diabetes mellitus Hypog-lycemic activity 

分 类 号：S886.9[农业科学—特种经济动物饲养] TQ463.5[农业科学—畜牧兽医]