出院后喂养方式对早产低出生体重儿生后3个月生长指标增长率的影响  

Effects of feeding patterns after hospital discharge on increase rates of growth indices in preterm and low-birth-weight infants within 3 months after birth

作　　者：吴繁[1] 崔其亮[1] 谭小华[1] 张慧[1] 高平明[2] 黄润忠 杨基龙 阮婉芬 黄志坚 瞿柳红[7] 丘小汕[8] 湛洁谊[9] 高树辉 

机构地区：[1]广州医学院第三附属医院儿科,广东广州510150 [2]佛山市妇幼保健院新生儿科,广东佛山528000 [3]佛山市顺德区妇幼保健院新生儿科,广东佛山528300 [4]广州市番禺区妇幼保健院新生儿科,广东广州511400 [5]佛山市顺德区第一人民医院新生儿科,广东佛山528300 [6]广州市妇女儿童医疗中心新生儿科,广东广州510623 [7]广州市花都区妇幼保健院新生儿科,广东广州510800 [8]中山大学附属第一医院新生儿科,广东广州510080 [9]广州医学院第一附属医院新生儿科,广东广州510120 [10]佛山市禅城区中心医院新生儿科,广东佛山528031

出　　处：《中国当代儿科杂志》2013年第2期129-132,共4页Chinese Journal of Contemporary Pediatrics

基　　金：广东省科技计划项目(粤科规划字[2011]97号);广州市科技计划项目应用基础研究专项重点项目(2011J4100046);广州市医药卫生科技项目(201102A213149)

摘　　要：目的通过研究早产儿出院后配方奶(PDF)与母乳(BM)、足月儿配方奶(TF)等不同喂养方式对早产低出生体重儿(LBWI)出院至生后3个月时的体重、身长、头围等生长指标增长率的影响,为早产LBWI出院后喂养方式的选择提供参考。方法广东省广州市、佛山市10家医院新生儿科出院的407例早产LBWI按照出院后喂养方式的不同,分为PDF组(n=258)、BM组(n=58)、TF组(n=91),观察各组在生后3个月时的体重、身长、头围等生长指标值,并计算和比较各生长指标较出生时的增长率。结果 PDF组在生后3个月时的体重、身长和头围分别大于BM组和TF组(P<0.05);体重和身长增长率分别大于BM组和TF组(P<0.05)。结论出院后予PDF喂养能使早产LBWI在生后3个月时的体重、身长增长率较BM、TF喂养者更大,从而具有较大的体重、身长值,但远期效果有待进一步研究。Objective To study the effects of post-discharge formula （PDF） for preterm infants, breast milk （BM） and term infant formula （TF） on increase rates of body weight, length and head circumference in preterm and low-birthweight infants （PLBWIs） from discharge to 3 months after birth, and to provide a reference for the choice of feeding pattern for PLBWIs. Methods A total of 407 PLBWIs discharged from the newborn departments of ten hospitals in Guangzhou City and Foshan City in Guangdong Province, China were chosen for this study. According to feeding pattern, they were assigned to three groups ： PDF-fed （ n = 258 ） , BM-fed （ n = 58 ） and TF-fed （ n = 91 ）. Their body weight, length and head circumference were measured at 3 months after birth, and the increase rates of growth indices relative to baseline values （at birth） were calculated and compared. Results At 3 months after birth, the PDF-fed group had significantly greater body weight, length and head circumference than the BM-fed and TF-fed groups （ P 〈 O. 05 ）. The increase rates of body weight and length were significantly higher in the PDF-fed group than in the BM-fed and TF-fed groups （ P 〈 O. 05 ）. Conclusions Compared with those fed with BM and TF after discharge, the PDF-fed PLBWIs have higher increase rates of body weight and length and show greater body weight and length at 3 months after birth. However, further study is needed to investigate the long-term effects.

关 键 词：低出生体重 喂养方式 生长发育 早产儿 婴儿 

分 类 号：R174[医药卫生—妇幼卫生保健]