醒脾养儿颗粒对肺炎继发腹泻患儿血清胃泌素、血浆胃动素及生长抑素水平的影响  

Effects of Xingpi Yang'er Granule on Serum Gastrin, Plasma Motilin, and Somatostatin Contents in Children Patients with Pneumonia Induced Diarrhea

作　　者：陈欣欣[1] 程玉先[1] 

机构地区：[1]山东省聊城市人民医院儿科,山东聊城252000

出　　处：《中国中西医结合杂志》2013年第2期155-158,共4页Chinese Journal of Integrated Traditional and Western Medicine

摘　　要：目的观察醒脾养儿颗粒对肺炎继发腹泻患儿血清胃泌素(gastrin,GAS)、血浆胃动素(moti-lin,MOT)及生长抑素(somatostatin,SS)的影响。方法选择2011年6月—2012年6月聊城市人民医院儿科住院的120例肺炎继发腹泻患儿,随机分为治疗组和对照组,每组60例,治疗组采用醒脾养儿颗粒治疗,对照组采用双歧杆菌乳杆菌三联活菌片治疗,另选择30名在我院体检健康的儿童作为健康组,观察病例组疗效及各组治疗前后GAS、MOT及SS水平。结果治疗组和对照组总有效率分别为95%和93.3%,差异无统计学意义(P>0.05)。与健康组比较,两患者组治疗前GAS、MOT均升高,SS降低(P<0.05)。与本组治疗前比较,两组治疗后GAS、MOT明显下降,SS升高(P<0.05)。与对照组同期比较,治疗组治疗后GAS、MOT降低,SS升高,差异均有统计学意义(P<0.05)。结论肺炎继发腹泻时胃肠激素的含量有明显的改变,醒脾养儿颗粒对肺炎继发腹泻患儿GAS、MOT、SS具有明显的调节作用。ObjectiveTo observe the effects of Xingpi Yang′er Granule （XYG） on serum gastrin （GAS）, plasma motilin （MOT）, and somatostatin （SS） in children patients with pneumonia induced diarrhea. MethodsRecruited were 120 children inpatients with pneumonia induced diarrhea at the Department of Pediatrics, Liaocheng People′s Hospital from June 2011 to June 2012. They were randomly assigned to two groups, the treatment group and the control group, 60 in each group. Those in the treatment group were treated with XYG, while those in the control group were treated with Live Combined Bifidobacterium and Lactobacillus Tablets. Besides, 30 healthy children who received physical examinations at our hospital were recruited as the healthy control group. The clinical efficacy, changes of GAS,MOT, and SS contents were observed. ResultsThe total effective rate was 950% in the treatment group and 933% in the control group, showing no statistical difference （P〉0.05）. Compared with healthy control group, the GAS and MOT contents increased, and SS decreased before treatment in the other two groups （P〈0.05）. Compared with the same group before treatment, GAS and MOT contents obviously decreased, and SS increased in the other two groups after treatment （P〈0.05）. Compared with the control group at the same time point, GAS and MOT decreased, and SS increased in the treatment group after treatment, showing statistical differences （P〈0.05）. ConclusionsThe levels of GAS, MOT, and SS were obviously changed in children patients with pneumonia induced diarrhea. XYG had obvious regulation on their GAS, MOT and SS contents.

关 键 词：醒脾养儿颗粒 肺炎继发腹泻 血清胃泌素 血浆胃动素 生长抑素 

分 类 号：R272[医药卫生—中医儿科学]