肝癌“湿热伏邪”——“癌毒”发病机制及疗法探讨  

Exploring the Pathogenesis and Therapy of Liver Cancer from "Damp-Heat Insidious Pathogen" to "Cancer Toxin"

作　　者：王书杰[1] 韦艾凌[1] 

机构地区：[1]湖南浏阳市中医医院肝病科,湖南浏阳410300

出　　处：《中国中西医结合杂志》2013年第2期266-269,共4页Chinese Journal of Integrated Traditional and Western Medicine

基　　金：国家自然科学基金资助项目(No.30960475)

摘　　要：分析慢性肝病(病毒性肝炎、肝硬化、肝癌)的致病因素——乙型肝炎病毒(HBV)的病邪属性及其致病特点,得出"湿热伏邪"这一概念,并以此为线索进行深入探讨。通过卫气营血辨证,分析湿热伏邪的传变过程中所导致不同的症候群以及新的病理产物如"痰"、"瘀"等,并阐释了痰、瘀作为枢纽因子,在肝络病变中起到的作用,最后形成湿热痰瘀互结壅盛之象,而形成"癌毒"。通过纵观慢性肝病发展,明确"湿热伏邪"作为疾病的始动因素,并贯穿全过程,总结出以清热化湿解毒为大法的治疗原则。From a macro level analysis of the attributes and pathogenic features of HBV， the main pathogenic factor for chronic liver diseases including viral hepatitis， cirrhosis， and liver cancer， the concept of damp heat insidious pathogen was obtained， according to which， in depth discussions were undertaken. Adopting syndrome typing of Wei （defense）， qi （vital energy）， Ying （nutrients）， and blood， the pathogens leading to different syndromes as well as new products such as pathological ＂sputum＂， ＂stasis＂ in the disease process were understood， and then， the pathological ＂sputum＂ and ＂stasis＂， as the hub， playing a role in chronic lesions of the liver collateral were explained. Finally the pathological ＂sputum＂ and ＂stasis＂ blend and form cancer toxin. Through a comprehensive understanding of the development of chronic liver diseases， it is clear that damp heat insidious pathogen， as its initiating factor， always exists in the whole process. We summed up heat clearing， dampness resolving， and detoxification was the principle for treating chronic liver disease

关 键 词：湿热伏邪 癌毒 肝癌 发病机制 清热化湿解毒 

分 类 号：R273[医药卫生—中西医结合]