老年肺结核患者治疗效果影响因素的Logistic回归分析  

Analysis of therapeutic efficacy and factors influencing the treatment outcome of geriatric tuberculosis patients

作　　者：周泽文[1] 胡代玉 李勤[3] 马婧婧[1] 王润华[1] 易静[1] 

机构地区：[1]重庆医科大学公共卫生与管理学院统计教研室,重庆400016 [2]重庆市结核病防治所 [3]重庆市疾病预防控制中心传染病预防与控制所

出　　处：《中国老年学杂志》2013年第4期894-896,共3页Chinese Journal of Gerontology

基　　金：国家自然科学基金(30872160);重庆市科委自然科学基金(2009BB5415)

摘　　要：目的探讨影响重庆市老年肺结核患者治疗效果的因素,为结核病的防治提供依据。方法以重庆市2011年1月1日至12月31日期间60岁以上肺结核患者为研究对象,连续动态收集老年结核病患者的人口学基本信息、患病情况及治疗相关情况,利用非条件Logistic回归筛选影响肺结核治疗效果的因素。结果研究纳入5 678例老年肺结核患者,患者治愈率为76.24%。单因素和多因素回归分析均显示,结核初治、2月末及5月末痰检结果阴性及全程督导管理模式是提高肺结核治愈率的关键因素,患有糖尿病和对结核常规治疗药物耐药是降低肺结核治愈率的主要因素。结论深入贯彻"全程督导"模式,及时积极地参与治疗、有效地定期随访以及合理搭配用药有助于提高老年肺结核患者治愈率。Objective To investigate the therapeutic efficacy and analyze the factors irffluencing on the treatment outcome of geriat- ric tuberculosis patients, and provide evidence for tuberculosis prevention and control. Methods 5 678 geriatric tuberculosis patients who took part in tuberculosis treatment in Chongqing from January 1,2010 to December 31,2010 were surveyed and patients data were collected as well. Logistic regressions were used to analyze the factors influencing the treatment outcome. Results The cure rate of geriatric tuberculosis patients was 76. 24%. The protective factors for treatment outcome included preliminary treatment, sputum negative after the treatment for 2 month and 5 month and directly-observed treatment strategy, diabetes and drug resistance were risk factors for treatment outcome. Conclusions To implement the directly-observed treatment strategy, treating the complications of patients actively, following up regularly, rational use of drugs and offering psychological care will contribute to improving the cure rate of geriatric tuberculosis patients.

关 键 词：肺结核 治疗效果 影响因素 

分 类 号：R521[医药卫生—内科学]