石英纤维/纳米羟基磷灰石/聚酰胺66复合生物材料的制备和性能  

Preparation and Properties of QF/n-HA/PA66 Composite Biomaterial

作　　者：陈抒天[1] 李鸿[1] 郝新彦[1] 王广妮[1] 樊晓霞[1] 严永刚[1] 

机构地区：[1]四川大学物理科学与技术学院,成都610064

出　　处：《材料研究学报》2013年第1期32-36,共5页Chinese Journal of Materials Research

基　　金：国家科技支撑计划项目2007BAE13B03;生物材料与制品开发四川省青年科技创新研究团队2011JTD0024资助项目~~

摘　　要：用挤出法制备石英纤维(quanz fibre,QF)/纳米羟基磷灰石(nano-hydroxyapatite,n-HA)/聚酰胺66(polyamide 66,PA66)复合材料(OF/n-HA/PA66),表征了其结构、形貌、力学性能和细胞毒性。结果表明:QF均匀地分散在n-HA/PA66中,且与PA66基体存在氢键结合;复合材料的力学性能随着石英纤维含量的增加而增大,当石英纤维含量为38%时复合材料的抗拉强度为81 MPa,抗压强度为190 MPa,抗弯强度为195 MPa(比人体皮质骨的高);n-HA/PA66基体所承受的载荷传递给QF纤维,纤维轴向传递使应力迅速扩散,这种传递作用在一定程度上起到了力的分散作用,从而增强了材料承受外力作用的能力,导致材料的弯曲强度、拉伸强度等力学性能的显著提高。QF/n-HA/PA66复合材料无细胞毒性,满足承重骨修复材料的要求。Quartz fibre/nano-hydroxyapatite/polyamide 66 （QF/n-HA/PA66） composite biomaterial was prepared by extrusion method in this study. The composition and morphology of the composite were characterized by FT-IR, XPS, XRD and SEM. The mechanical strength was tested by universal material testing machine and the cytotoxicity was evaluated using L929 cell line. The results showed that QF was uniformly dispersed in n-HNPA66, with the hydrogen bond formed between QF and PA66. The mechanical strength of QF/n-HA/PA66 composite biomaterial was improved with the increase of the quartz fibre content. When the QF content （mass fraction） increased to 38%, the composite＇ tensile strength, compressive strength and flexural strength reach 81 MPa, 190 MPa and 195 MPa respectively, higher than those of human cortical bone. The load bearing on the n-HA/PA66 composite matrix transferred to QF fibre, and the load bearing rapidly diffused in all directions because of stress transmission along the axial direction of the QF fibre. While this stress transmission had an efficacy of load disperse in some extent, thus enhanced the capability of the composites adapting to Ioadings, and the mechanical strength of QF/n-HA/PA66 remarkably increased. After 3 days of culture with the L929 cell line, no negative effects of the composite on cell viability were observed, demonstrating that the composite had no cytoxicity.

关 键 词：复合材料 石英纤维 纳米羟基磷灰石 聚酰胺66 生物材料 细胞毒性 

分 类 号：TB332[一般工业技术—材料科学与工程]