海南省2011年疑似预防接种异常反应监测分析  

Surveillance of suspected adverse events in persons after vaccination in Hainan province in 2011

作　　者：陈碧玉[1] 曾雪霞[1] 莫少雄[1] 黄雅靖[1] 李俊[1] 孙莲英[1] 

机构地区：[1]海南省疾病预防控制中心传染病预防控制所,海南海口570203

出　　处：《中国热带医学》2012年第12期1466-1468,1471,共4页China Tropical Medicine

基　　金：海南省自然科学基金项目(No.310176)

摘　　要：目的评价海南省AEFI监测系统运转质量,指导AEFI调查处置工作。方法通过全省AEFI监测系统收集2011年AEFI个案资料,采用描述流行病学分析方法对个案病例的流行病学特征进行分析。结果 2011年全省18个市县共报告AEFI病例1019例,报告发生率2.60/万剂,市县报告覆盖率100%,AEFI病例48小时内及时报告率和及时调查率分别为94.50%和98.82%。AEFI分类一般反应占70.17%,异常反应占25.71%,其他反应占4.12%。异常反应主要以过敏性皮疹、卡介苗淋巴结炎和荨麻疹为主,占85.87%。AEFI病例中接种后≤1天发生者占80.18%。结论海南省AEFI监测系统维持较高敏感性,病例报告、调查和处置等监测指标均达到国家要求,有待进一步加强接种技能培训,接种前告知和接种后留观等措施。Objective The study is to analyze the occurrence features of adverse events following immunization （AEFI） in China, and to evaluate the implementation of AEFI surveillance system, provide a basis for coping with AEFL Methods The AEFI data in 2011 were collected through AEFI Surveillance. The descriptive methodology is used in this study. Results 1019 AEFI cases occurring in 2011 were reported. The reported AEFI incidence rate was 2.60por 10 thousand doses, and the coverage rate of counties was 100%. The timely report rate within 48 hours was 94.50%, the timely investigation rate within 48 hours was 98.84%, 70.17% cases were commom, minor reactions, 25.71% were rare, serious reactions and others were 4.12%. Most of serious reactions were Anaphylactic Rash, suppurative lymphadenitis, and nettle rash,that occupied 85.87%. 80.18% of AEFI cases occurred 〈 1 day after vaccination. Conclusion The surveillance of AEFI has good sensitivity. The cases were investigated and handled in time. It is important to enhance the standardization of vaccination, informed for the subjects to find and handle with cases in time.

关 键 词：疑似预防接种异常反应 检测 疫苗 

分 类 号：R186[医药卫生—流行病学]