丙泊酚与地佐辛在治疗性内镜逆行胰胆管造影术中的应用  

Application of propofol in combination with dezocine in therapeutic ERCP

作　　者：赵帅 韩钧凌[2] 

机构地区：[1]解放军第425中心医院医务处,海南三亚572000 [2]解放军第187中心医院消化内科,海南海口570200

出　　处：《中国热带医学》2012年第12期1555-1556,共2页China Tropical Medicine

摘　　要：目的观察丙泊酚与地佐辛联合麻醉在治疗性内镜逆行胰胆管造影术(ERCP)检查中应用的可行性。方法选286例ASA(美国麻醉医师协会)Ⅰ～Ⅲ级,择期行治疗性ERCP的患者分成P组(丙泊酚麻醉组)和PD组(丙泊酚与地佐辛联合麻醉组),每组143例。分别记录两组患者术前、术中、术后的MAP、HR、SPO2、丙泊酚的用量及手术持续时间、术毕患者苏醒时间、麻醉期间的不良反应如舌后坠、肢体扭动、呼吸抑制等。结果 P组术中MAP、HR变化与术前、PD组比较差异有统计学意义(P<0.05),PD组苏醒、离院时间及丙泊酚用量小于P组(P<0.05)。结论丙泊酚联合地佐辛在治疗性ERCP中应用是安全有效的,值得推广。Objective To investigate the quality and safety of propofol in combination with dezocine in therapeutic Endosecopic retrograde eholangiopangiopanereatography （ERCP）. Methods Two hundrend eighty-six patients with ASA I ~ Ⅲ underwent therapeutic ERCP and were randomly assigned into propofol groups （Group P） consisted of 143 cases and treated with propofol, and dezocine group （Group P＋D） also consisted of 143 cases and treated with propofol combined with dezocine.. The parameter, such as levels of MAP, HR, SPO2, the dose of propofol ,the recovery time, discharged time were observed and recorded. Results The changes of levels of NBP, HR, SPO2 were less than the base line in propofol group during operation （P 〈 0.05） =, and the recovery time, discharged time and the dose of propofol in group P＋D were less than that in group P（P 〈 0.05）. Conclusions Propofol combined with dezocine is safe and effective fro application in therapeutic ERCP.

关 键 词：丙泊酚 地佐辛 内镜逆行胰胆管造影术 

分 类 号：R971.2[医药卫生—药品]