异腈参与的多组分反应研究进展  

Multi-component Reaction Based on Isocyanides

作　　者：刘学巍[1] 甘海峰[1] 钱祥均[1] 邹宝华[1] 仲蕙[1] 郭凯[1] 

机构地区：[1]南京工业大学生物与制药工程学院,南京211816

出　　处：《化学通报》2013年第2期107-112,共6页Chemistry

摘　　要：多组分反应由于反应本身的经济性和生态价值,越来越受到人们的重视。异腈的亲电和亲核反应均发生在碳原子上,因此在多组分反应中具有重要作用。本文就近年来有异腈参与的多组分反应进行了综述,主要阐述了Ugi反应和Passerini反应及其他含异腈参与的多组分反应的机理、研究开展及应用情况。Multi-component reactions （MCRs） have attracted lots of interest and been the focus of many synthetic chemists due to their intrinsic economic and ecological value. Since both electrophilic reaction and nucleophilic reaction are performed via the carbon atom, isocyanide plays a significant role in MCRs. In this paper, progresses of MCRs involved isocyanide in recent years, especially about the mechanism, research progress and anolication of U^i reaction~ nnd Pn^garlni raAc, tinn~ w^rp rli~,,~A

关 键 词：多组分反应 异腈 Passerini反应 Ugi反应 

分 类 号：TQ226.6[化学工程—有机化工]