多指标正交试验法优选温胃阿亚然及片的提取工艺  

Optimization of Extraction Technology for Wenwei Ayaranji Tablets by Multi-index Orthogonal Test

作　　者：毛艳[1,2] 顾政一 贺金华 蔡晓翠 康雨彤 严欢 戎晓娟 

机构地区：[1]石河子大学药学院,新疆石河子832002 [2]新疆维吾尔自治区药物研究所,乌鲁木齐830004

出　　处：《中国实验方剂学杂志》2013年第4期53-56,共4页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：新疆维吾尔自治区重大科技专项(201130105-4)

摘　　要：目的:优选温胃阿亚然及片的提取工艺。方法:以芦荟苷、芦荟大黄素、总葫芦素含量和浸膏得率的综合评分为指标,采用L9(34)正交设计考察乙醇体积分数、提取次数及加醇量对温胃阿亚然及片提取工艺的影响。结果:最佳提取工艺为加15倍量80%乙醇提取3次,每次1 h。结论:优选的提取工艺简单、可行,可用于该制剂的工业化生产。Objective： To optimize extraction process of Wenwei Ayaranji tablets. Method： With the content of aloin, aloe-emodin, total cucurbitacin and extract yield as indexes, extraction technology of Wenwei Ayaranji tablets was optimized by orthogonal design by ethanol concentration, extraction times and ethanol amount. Result： Optimum extraction technology was as following： extracted 3 times with 15 times the amount of 80% ethanol, 1 h each time. Conclusion： This optimized extraction technology was simple and feasible, it could be used for industrial production of the preparation.

关 键 词：温胃阿亚然及片 提取工艺 正交试验 芦荟苷 芦荟大黄素 总葫芦素 

分 类 号：R283.6[医药卫生—中药学]