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作 者:谈晓轶[1] 池霞[1] 梁沂[1] 徐亚琴[1] 王丽[1] 周影[1] 张蕾[1]
机构地区:[1]南京医科大学附属南京妇幼保健院儿童保健科,江苏南京210004
出 处:《南京医科大学学报(自然科学版)》2012年第12期1727-1730,共4页Journal of Nanjing Medical University(Natural Sciences)
基 金:国家自然科学基金资助(30801255);江苏省医学重点人才资助(RC2011022);南京市医学科技发展项目(201108007);南京医科大学科技发展基金(2010NJMU0024)
摘 要:目的:探讨4~5岁儿童注意力持续测试软件(Conners’kiddie continuous performance test,K-CPT)在诊断学龄前儿童注意缺陷多动障碍(attention deficit hyperactivity disorder,ADHD)中的临床应用价值。方法:以美国精神障碍诊断和统计手册第4版(DSM-IV)为诊断标准,对41例临床诊断ADHD的儿童,进行Conners’父母用简明症状问卷(parent symptom questionnaire,PSQ)调查和K-CPT评估。结果:K-CPT评估结果与DSM-IV诊断标准比较,在ADHD检出率方面无显著性差异(P>0.05)。K-CPT诊断学龄前ADHD的灵敏度为73.3%,特异度为81.8%,假阳性率为18.2%,假阴性率为26.7%,符合率为75.7%,Kappa值为0.470(P<0.001),K-CPT与金标准之间存在中度一致性。K-CPT和PSQ在患儿阳性检出率方面,差异均无显著性(P>0.05)。结论:K-CPT测试结果可作为客观诊断指标,用于学龄前ADHD的协助诊断。Objective:To explore the clinical application of Conners’ kiddie continuous performance test(K-CPT) on diagnosis in preschool children with attention deficit hyperactivity(ADHD).Methods:Using the diagnostic and statistical manual of Mental disorders(DSM-IV) as a gold standard,K-CPT and parent symptom questionnaire(PSQ) were tested in 41 cases of preschool children with ADHD and evaluated.Results:Compared with DSM-IV,the sensitivity for K-CPT in diagnosing ADHD reached 73.3%,specificity for K-CPT was 81.8%,the false negative rate was 26.7%,and the false positive rate was 18.2%.The coincidence rate amounted 75.7%.The value of kappa was 0.470(P 0.001).There is no significant difference(P 0.05) in the detection rate of KCPT and PSQ.Discussion:K-CPT could be used as an objective diagnostic tool and applied in diagnosis of preschool ADHD.
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