新疆维吾尔族自然长寿老人加速度脉搏波研究  

Study of the acceleration plethysmogram in Uygur natural longevous in Xinjiang

作　　者：谢姆西凯麦尔.奥布力喀斯木 陈凤辉[1] 程祖亨[1] 李京宴[1] 玛依拉.吾甫尔 

机构地区：[1]新疆医科大学第一附属医院心脏中心,乌鲁木齐830054

出　　处：《北京医学》2013年第2期81-84,共4页Beijing Medical Journal

基　　金：国家自然科学基金(31160215)

摘　　要：目的探讨新疆和田地区维吾尔族自然长寿老人加速度脉搏波(APG)可能的影响因素。方法以新疆和田地区120例维吾尔族自然长寿个体(≥90岁)为研究对象(长寿组),以53例70岁前自然死亡的同地区、同民族个体作为对照组。对其进行查体,并行动态血压、加速度脉搏波、血脂、血糖等检查。结果年龄、体质指数、高密度脂蛋白胆固醇、b/a、c/a、d/a及△年龄(血管推定年龄-实际年龄)在长寿组与对照组之间的差异有统计学意义(P<0.05),长寿组血管弹性及静脉血液循环优于对照组,24h动态收缩压、24h动态舒张压、总胆固醇、低密度脂蛋白胆固醇、甘油三酯、空腹血糖及e/a在长寿组与对照组的差异无统计学意义(P>0.05);年龄、体质指数、高密度脂蛋白胆固醇均可影响△年龄。结论长寿组动脉硬化程度较对照组明显,但动脉硬化的进程较为缓慢,保持相对良好的血管弹性可能是长寿原因之一。Objective To analyze the acceleration plethysmogram （APG） of the Uygur natural longevous from Het-ian of Xinjiang, and to investigate the factors associated with the APG. Methods 120 healthy individuals over 90 years old and 53 control individuals who died in their 65-70 years old were recruited. The physical examination, ambulatory blood pressure, APG, serum lipid, serum glucose levels were measured. Results The age, BMI, serum HDL-C, b/a, c/a, d/a and △age, all were significantly different between the longevous group and the control group （P 〈 0.05）, the vasoac-tivity and venous blood circulation of the longeval group was better than the control group, while the 24 h-SBP, 24 h-DBP, TC, LDL-C, TG, serum glucose and e/a were not significantly different between the two groups （P 〉 0.05）. Age, BMI, serum HDL-C level, all could influence the △age. Conclusion The severity of atherosclerosis is more obvious in the longevous group than the control group, but the process progress is slower than the control group. It shows that keeping vasoactivity in good condition maybe one cause of longevity.

关 键 词：加速度脉搏波 维吾尔族 长寿 动脉硬化 

分 类 号：R195[医药卫生—卫生统计学]