酚苄明治疗良性前列腺增生症伴急性尿潴留的临床作用探讨  

Effect of Dibenzyline in the Treatment of Benign Prostatic Hyperplasia Patients with Acute Urinary Retention

作　　者：巢仙亮 罗琴[1] 

机构地区：[1]上高县人民医院,江西上高336400

出　　处：《亚太传统医药》2013年第2期167-168,共2页Asia-Pacific Traditional Medicine

摘　　要：目的:探讨非选择性肾上腺素能受体阻滞剂酚苄明(Dibenzyline)对良性前列腺增生症(BPH)伴急性尿潴留患者的治疗作用。方法:将155例BPH伴急性尿潴留患者随机分为治疗组和对照组。患者均行保留导尿,口服抗生素治疗,治疗组加用酚苄明10mg,2次/d,连续服用3天。72h后拔除导尿管。结果:拔除导尿管后46%(72/155)的患者能自行排尿。治疗组有效率为59%(51/86),对照组为30%(21/69),两组比较差异有显著性(P<0.05)。结论:对BPH伴急性尿潴留患者应用酚苄明治疗,可提高早期拔除导尿管后患者自行排尿的成功率,且副作用相对较小,价格便宜,适合临床推广应用。Objective：To evaluate the clinical efficacy of adrenoceptor antagonist（Dibenzyline） in the treatment of benlign prostatic hyperplasia（BPH） patients with acute urinary retention. Methods：One hundred and fifty-five BPH patients with acute retention of urine were randonmLy divided into treatment group and control group. Eighty-six patients in treatment group and sixty-nine patients in control group. All the patients were treated with indwelling catheter, oral antibiotics and the patients in treatment group Dibenzy-line 10mg twice a day for 3 days. The catheter was removed after 72 hours of treatment. Results： After removal of the catheter, 46 % （72/155） of patients voided successfully. The effect rates were 59 % （51/86） in the Dibenzyline treatment group and 30 % （21/ 69） in the control group（P〈0.05）. Conclusion： Treatment with Dibenzyline was effective in raising the success rate of voiding without catheter after an episode of acute urinary retention. Meanwhile, it was very cheap, security was high relatively. So, it is suitable to be widely used.

关 键 词：前列腺增生症 酚苄明 急性尿潴留 

分 类 号：R697.3[医药卫生—泌尿科学]