反复腹痛患儿幽门螺杆菌感染的影响因素分析  

Analysis on influencing factors of Helicobacter pylori infection in children with recurrent abdominal pain

作　　者：高静云[1] 张天哲[2] 张铁民 段俊梅[2] 

机构地区：[1]河北省唐山市妇幼保健院儿科,063000 [2]华北煤炭医学院预防医学系流行病与卫生统计学学科 [3]唐山钢铁公司医院儿科

出　　处：《中国妇幼保健》2013年第6期951-955,共5页Maternal and Child Health Care of China

摘　　要：目的:探讨反复性腹痛患儿幽门螺杆菌(HP)感染相关因素,为预防幽门螺杆菌感染提供依据。方法:选择反复慢性腹痛患儿196例,利用13C-尿素呼气试验及HP粪便抗原检测确定反复腹痛儿童Hp感染情况,此两种检测均阳性者作为病例组,阴性者作为对照组;采用统一编制的调查表收集被调查者的相关资料。结果:196例反复腹痛患儿中感染HP 85例(病例组),感染阳性率为43.4%。单因素分析两组在年龄、病程、居住地的分布差异无统计学意义(P>0.05),而男女性别构成差异有统计学意义(P<0.05);是否与家人同睡、母亲文化程度、其他照顾者是否有胃病史均与HP感染有关(P<0.05)。经多因素非条件Logistic回归分析,控制混杂因素后结果仍显示性别、是否与家人同睡、其他照顾者胃病史有无3个因素与感染有关,即性别为女性、独睡、被除父母外无胃病史的其他照顾者照看的儿童HP感染的危险性降低。结论:此次调查显示反复腹痛儿童HP感染与性别、是否与家人同睡和其他照顾者胃病史有关联。Objective： To explore the related factors of Helicobacter pylori （HP） infection in children with recurrent abdominal pain, and provide a basis for preventing HP infection. Methods： A total of 196 children with recurrent abdominal pain were selected, 13C - urea breath test and HP stool antigen test were used to detect HP infection status in the children ; the children with both positive results of the two tests were designed as case group, and the children with both negative results were designed as control group; a unified questionnaire was used to collect related data of respondents. Results： Among 196 children with recurrent abdominal pain, 85 children were found with HP in- fection （ease group）, the positive rate of HP infection was 43.4%. The results of univariate analysis showed that there was no statistically significant difference in age, course of the diseases, and distribution of place of residence between the two groups （ P 〉 0. 05 ）, but there was statistically significant difference in proportion of gender between the two groups （ P 〈 0. 05 ） ; sleeping with family members or not, maternal educational level, and having history of stomach illness or not of other carers were correlated with HP infection （ P 〈 0.05 ） . After control- ling confounding factors, the results of multivariate non - conditional logistic regression analysis showed that age, sleeping with family mem- bers or not, and having history of stomach illness or not of other carers were related to HP infection, which meant that the risk of HP infection among girls, the children sleeping alone, and the children whose carers had no history of stomach illness decreased. Conclusion： The sur- vey shows that HP infection among children with recurrent abdominal pain is correlated with age, sleeping with family members or not, and having history of stomach illness or not of other eaters.

关 键 词：儿童 反复性腹痛 幽门螺杆菌 危险因素 

分 类 号：R725[医药卫生—儿科]