贵阳市327名就诊儿童幽门螺杆菌感染血清流行病学调查  

Seroepidemiological study of Helicobacter pylori infection in 327 hospitalized children in Guiyang City

作　　者：刘丽[1] 何利华[2] 张建中[1] 

机构地区：[1]贵州省疾病预防控制中心妇幼保健所,贵阳550004 [2]中国疾病预防控制中心传染病预防控制所,北京102206

出　　处：《贵州医药》2012年第6期502-504,共3页Guizhou Medical Journal

基　　金："十一五"国家科技支撑计划"消化;妇儿等常见病防治研究"重点项目(2007BAI04B02)

摘　　要：目的了解贵阳市就诊儿童幽门螺杆菌(HP)的感染状况,进行血清流行病学调查。方法对14岁以下的就诊儿童进行快速幽门螺杆菌尿素酶抗体检测。结果327名就诊儿童HP感染率是22.02%,男性感染率20.19%,女性25.44%,两者差异无显著性(P>0.05);各年龄组间儿童HP感染差异没有统计学意义(P>0.05);自身免疫系统疾病中HP感染率为30.30%,非自身免疫系统疾病为21.09%,未观察到与HP感染的明显相关性(P>0.05);消化系统疾病HP感染率是50%,明显高于非消化系统疾病HP感染率(P<0.05)。结论HP感染相关消化道症状是影响该地区儿童就诊的重要相关因素;对低年龄组儿童因HP感染的就诊行为值得关注。Objective Undertake the seroepidemiological survey of Helicobacter pylori（H.pylori） in Guiyang city in order to learn about H.pylori infection in the hospitalized children in the area. MethodsH.pylori antibodies were detected by H.pylori Urease Immunogold Testing Kit among 327 children below the age of fourteen. Results22.02 % of the 327 children were seropositive for H.pylori.Positive rates of boys and girls were 20.19 and 25.44%,respectively,and there were no statistically significant difference（P〉0.05）.There were also no statistically significant in different age group（P〉0.05）.H.pylori positive rate in children with gastro-intestinal symptoms（50%） was much higher than that of others with non-gastro-intestinal diseases（P〉0.05）.There was no significant difference（P〈0.05） in the seropositivity of H.pylori infection between autoimmune diseases and others. ConclusionH.pylori associated gastro-intestinal symptoms is an important factor that influenced children on going to see the doctors.The behaviour of low-age children to be hospitalized because of H.pylori infection should be paid attention to in this area.

关 键 词：儿童 幽门螺杆菌 流行病学调查 

分 类 号：R725.7[医药卫生—儿科]