透刺电针治疗神经根型颈椎病临床观察及对患者血浆TNF-α和IL1β的影响  

Clinical Observation of Electroacupuncture Point-through-point Treatment of Nerve Root Type of Cervical Spondylosis and Influence of TNF-α and IL1β

作　　者：万碧江[1] 黄伟[2,3] 张压西[1] 陈汉跃[1] 张荒生[1] 陈培红[1] 肖凤英[1] 付兰萍[1] 张蕾[1] 

机构地区：[1]武汉市中医院,湖北武汉430000 [2]湖北中医药大学临床医学院,湖北武汉430000 [3]湖北省中医院,湖北武汉430000

出　　处：《中华中医药学刊》2013年第2期373-375,共3页Chinese Archives of Traditional Chinese Medicine

基　　金：武汉市卫生局科研资助项目(WZ11C05)

摘　　要：目的:观测透刺电针对神经根型颈椎病(CSR)患者治疗前后血浆TNF-α、IL1β含量的影响。方法:将160例CSR患者随机分为3组,透刺电针组60例,采用透刺电针治疗;夹脊电针60例,采用电针颈夹脊治疗;颈复康组40例,予口服颈复康治疗。评定临床疗效,并检测患者治疗前后血浆TNF-α和IL1β的变化。结果:(1)透刺电针组痊愈率68.9%,总有效率100%;电针夹脊组痊愈率39.2%,总有效率为91.61%;颈复康组痊愈率22.8%,总有效率为82.8%;3组痊愈率、总有效率比较,经统计学处理,有极显著性差异(X2=20.1、9.7,P<0.01)。(2)治疗后3组血浆TNF-α、IL1β含量均呈下降趋势,但透刺电针组明显降低,与治疗前比较,有极显著差异(P<0.01),与电针夹脊组、颈复康组比较,有显著性差异(P<0.05)。颈复康组对患者血浆TNF-α的降低优于电针夹脊组,电针夹脊组对血浆IL1β含量的调节优颈复康组。结论:透刺电针的临床疗效明显优于电针夹脊组和颈复康组;透刺电针能调节神经根型颈椎病患者血浆TNF-α和IL1β恢复平衡,从而减少炎症反应,达到抗炎止痛的目的。Objective ： To observe the effect of point - through - point electroacupuncture on nerve root type of cervical disease （CSR） patients and the influence on plasma levels of TNF - ot and IL1β. Methods ：160 cases of CSR patients were randomly divided into 3 groups. 60 cases of point - through - point electroacupuncture group ,which was treated point - through - point electroacupuncture; 60 cases were treated with penetration needling Jiaji points ; 40 cases in Jingfukang group were treated with oral Jingfukang treatment. Assessment of clinical efficacy, and .the changes of TNF - α and IL1β were observed before and after treatment. Results ： （ 1 ） The cure rate of point - through - point electroaeupuneture group was 68.9%, the total efficiency was 100% ; in electroacupuneture at Jiaji acupoints group, the cure rate was 39.2%, the total efficiency was 91.61% ; in Jingfukang group, the cure rate was 22.8%, the total effective rate was 82.8% ; comparison of cure rate and the total efficiency among the three groups had significant difference （ X^2 = 20.1, 9.7, P 〈 0. 01 ）. （2）In three groups after the treatment, plasma levels of TNF - α and IL1β were decreased, but the point - through- point electroaeupuneture group were significantly decreased, compared with that before treatment, there was a significant difference （P 〈 0.01 ）, compared with electroacupuncture at Jiaji acupoints group and Jingfukang group, there was significant difference（ P 〈 0. 05 ）. Jingfukang group was superior to the Jiaji acupeints group on plasma TNF - α level decrease, and IL1β regulation in electroacupuncture at Jiaji group was better than that in Jingfukang group. Conclusion ： The clinical efficacy of acupuncture is better than electroacupuncture Jiaji group and Jingfukang group; penetration acupuncture can regulate levels of TNF - α and IL1β of the nerve root type of cervical spondylosis patients to restore balance, thereby it can reduce inflammatory reaction and obtain the anti - inflammatory pu

关 键 词：神经根型颈椎病 透针电针 临床观察 TNF-Α IL1β 

分 类 号：R245.97[医药卫生—针灸推拿学]