2011年深圳市华侨城医院疑似预防接种异常反应数据分析  

Data Andysis On Adverse Events Following Immunization of Shenzhen OCT Hospital in 2011

作　　者：胡春明[1] 张功模[1] 郑琴[1] 

机构地区：[1]深圳华侨城医院,广东深圳518053

出　　处：《中国初级卫生保健》2013年第2期55-57,共3页Chinese Primary Health Care

摘　　要：目的了解深圳华侨城医院2011年疑似预防接种异常反应(AEFI)的发生情况,评价各类疫苗的安全性,及时发现引起AEFI的原因并采取纠正措施。方法采用描述性流行病学统计方法,对AEFI监测数据进行分析与评价。结果 2011年深圳华侨城医院开展预防接种的疫苗共有17类38种,疫苗接种16181人次,其中发生AEFI35例,发生率为2.16‰。涉及17种疫苗,其中白破疫苗AEFI发生率最高(32.61‰),无细胞百白破疫苗AEFI发生数居首位(9例,占25.71%)。反应类型:一般反应占54.29%(多为发热/红肿/硬结),异常反应占37.14%(多为皮疹),偶合症占8.57%;临床损害:发热/红肿/硬结占60.00%,皮疹占34.29%,血管性水肿占5.71%。病例主要发生在小年龄段人群(≤2岁占74.29%)。发生时间主要集中在5～10月份(77.14%),多在接种后l天内发生(88.57%)。结论深圳华侨城医院预防接种服务良好,各类疫苗的安全性比较高,但预防接种人员应不断学习,提高自身素质,加强AEFI监测工作,减少AEFI的发生。OBJECTIVE To know occurrence of adverse events following immunization（AEFI） of Shenzhen OCT Hospital in 2011, evaluate the safety of the vaccine, find out the reason of AEFI and take corrective actions. METHODS Use descriptive epidemiological statistical method to analyze and evaluate the AEFI monitoring data. RESULTS In 2011, Shenzhen OCT Hospital carried out 17 kinds （38 species） of vaccination on 16 181 persons. There are 35 examples of AEFI with the incidence of 2.16%o involving 17 kinds of vaccines. The incidence of the Diphtheria Tetanus vaccine（DT） vaccine is the highest（32.61%~）, the number of diphtheria tetanus acellular pertussis（DTaP） combined vaccine AEFI heads the list（9 cases, 25.71%）. As to the reaction type, the rate of general reaction was 54.29%（more for fever/red/callosity）, the rate of abnormal reaction is 37.14%（more for skin rash）, the rate of coupling disease is 8.57%, the rate of Clinical damage on fever/red/callosity is 60.00%, the rate of skin rash occupied 34.29%, the rate of angioedema is 5.71%. Cases mainly happened in young age（the occurrence rate of the 2 years old or less is 74.29%）. The time of occurrence is mainly concentrated in May to October（77.14%） and they usually occurred within 1 d after inoculation（88.57%）. CONCLUSION The service of Shenzhen OCT Hospital vaccination is good, the safety of all kinds of vaccine is high, but the staff of vaccination should keep learning and improve their own skill. We should strengthen the monitoring of AEFI and reduce occurrence rate of AEFI happen. Key words AEFI; data analysis; monitor

关 键 词：疑似预防接种异常反应 数据分析 监测 

分 类 号：R186[医药卫生—流行病学]