1422例荧光支气管镜检查结果回顾性分析  

Retrospective analysis of fluorescence bronchoscopy results of 1422 cases

作　　者：李王平[1] 金发光[1] 穆德广[1] 傅恩清[1] 谢永宏[1] 孙瑞琳[1] 

机构地区：[1]第四军医大学唐都医院呼吸内科,陕西西安710038

出　　处：《中华肺部疾病杂志（电子版）》2013年第1期7-9,共3页Chinese Journal of Lung Diseases(Electronic Edition)

基　　金：陕西省攻关项目(编号:2010K16-04-08);军队临床重点项目(编号:2010GXJS081)

摘　　要：目的探讨和评价荧光支气管镜在肺部疾病尤其是肺癌及支气管结核诊断中的价值。方法选择第四军医大学唐都医院呼吸内科2010年3月至9月支气管镜室使用荧光支气管镜检查的1422例临床资料,其中男性863例(60.69%),女性559例(39.31%);年龄最大86岁,最小4岁,平均57.84岁。分析了1422例荧光支气管镜检查的镜下及病理活检结果。结果支气管镜下白光与荧光均呈明显异常改变者,病理活检结果包括恶性病变,支气管结核、肉芽肿病变等改变;白光下异常,荧光镜下正常者,活检未发现1例恶性病变。白光下正常(包括黏膜轻度充血、肿胀者)而荧光镜下异常者,活检发现中-重度不典型增生1例;结论荧光支气管镜对于气管内明显可见并怀疑恶性病变的诊断价值不大,但黏膜荧光改变的程度可能有助于良、恶性病变的镜下鉴别。Objective To discuss and evaluate the value of diagnosis of fluorescence bronchoscopy in pulmonary diseases, especially lung and bronchus tuberculosis. Methods 1422 patients undergoing fluorescence bronchoscopy were enrolled from March 2010 to September in Department of Respiratory Disease, Tangdu Hospital ,Fourth Military Medical University. In 1422 cases, 863 cases were male （60.69%） , 559 cases were women （39.31%） ; The oldest was 86 years old, the youngest was 4 years old, the average was 57.84 years old. Pathologic biopsy results and traits of fluorescence bronchoscopy of 1422 cases were analyzed retrospectively. Results Both significantly abnormal changes in bronchoscopy white light and with fluorescence, the biopsy results included malignant lesions, bronchial tuberculosis, granulomatous disease, etc; Which abnormal in white light, but normal in fluorescence, none was diagnosed as malignant lesions. Which normal in white light（ including mild congestion, swelling） , but abnormal in fluorescence, one case was discoved as middle-severe dysplasia. Conclusion There is no distinct diagnostic value of fluorescence bronchoscopy for those visible and suspectable malignant lesions, but the degree of mucosa fluorescence change might help us identify the benign and malignant lesions in bronchscopy.

关 键 词：荧光支气管镜 白光 荧光 病理诊断 

分 类 号：R563[医药卫生—呼吸系统]