92例青壮年糖尿病临床分析  

Clinical analysis of the characteristics of diabetes mellitus in 92 middle-aged patients

作　　者：陶文玉[1] 李奕平[1] 徐凡[1] 

机构地区：[1]云南省第二人民医院内分泌科,昆明650021

出　　处：《重庆医学》2013年第6期642-644,共3页Chongqing medicine

摘　　要：目的分析92例青壮年糖尿病患者临床情况。方法对青壮年糖尿病患者的糖尿病分型、就诊主诉等临床资料进行分析。结果 92例患者中,初诊共70例(76.1%);其中42例体检或其他合并症或并发症就诊时发现血糖高(45.7%)。2型糖尿病(T2DM)共78例(84.8%)。在入院时血糖甚高和糖化血红蛋白较高,部分已有眼病、肾病和神经病变等并发症。T2DM合并高血压15例,男9例;合并血脂代谢紊乱33例(35.9%),男21例;T2DM肥胖患者24例(26.1%),男18例。T2DM糖尿病家族史占31.5%。1型糖尿病(T1DM)患者C肽平均水平处于胰岛β细胞功能衰竭破坏水平,胰岛细胞抗体(ICA)阳性率占77.8%;T1DM、GDM、糖尿病合并妊娠使用胰岛素治疗,对超重的T2DM和IGT患者使用二甲双胍片或胰升糖素样多肽1(GLP-1)类似物治疗控制体质量指数(BMI),其他T2DM患者仍使用胰岛素或(和)联合口服降糖药者51例(55.4%)。结论青壮年糖尿病患者中,大部分为初诊患者,而且相当高的比例无糖尿病症状,故应普及糖尿病知识教育,加强高危人群的筛查,提高青壮年尤其对男性青壮年糖尿病患者的检出率,及早诊断和治疗。Objective To analyze the clinical characteristics of diabetes mellitus （DM） in 92 middle-aged patients. Methods The clinical data of 92 patients with diabetes were analyzed. Results 70 cases diagnosed were preliminary,in which 42 cases were diagnosed in physical exam or other diseases. 78 cases were type 2 DM （T2DM）. The cases had high plasma glucose, HbAlc and some diabetic complications. There were hypertension, lipid disorders （35.9 % ） and obesity （26.1% ） occurred in T2DM patients. Positive family history was found in 31.5% of T2DM cases. In type 1 DM （T1DM） cases,C-peptide level showed the function of pancreatic β-eells had failed,and positive rate of β-cells antibodies was 77.8 %. Insulin treatment was selected to T1DM,GDM and T2DM complicated pregnancy. To obese cases,metformin and glucagon like peptide -1 analogue were used to control body mass index. Conclusion In middle-aged DM patients,most cases diagnosed were preliminary and had no obvious diabetic symptoms. We should do more education about diabetic knowledge in wide populations for diagnosing DM patients earlier and taking effective measures in

关 键 词：糖尿病 青壮年 临床分析 

分 类 号：R587.1[医药卫生—内分泌]