微骨折术联合玻璃酸钠注射修复膝关节软骨损伤  

Clinical Effect of Microfracture Combined with Hyaluronic Acid Injection to Repair Knee Joint Cartilage Injury

作　　者：付昌马 钱春生 章有才 

机构地区：[1]安徽省合肥市第三人民医院骨科,安徽合肥230022

出　　处：《实用骨科杂志》2013年第2期109-111,共3页Journal of Practical Orthopaedics

基　　金：合肥市科技局重点科研项目(合科2012127号)

摘　　要：目的研究关节镜下微骨折术(microfracture,MF)联合玻璃酸钠(hyaluronic acid,HA)注射修复膝关节软骨损伤患者的治疗效果。方法 收集2011年4月至2012年9月在合肥市第三人民医院关节镜手术治疗的40例膝关节软骨损伤患者,其中外伤导致的软骨损伤9例,骨关节炎(退变)导致的软骨损伤31例。对40例膝关节软骨损伤患者采用关节镜下微骨折术,缺损面积0.5-9 cm2,平均3.3 cm2;术后立即注射玻璃酸钠20 mg,术后第1周,第2周均注射HA 20 mg;术后8周膝关节功能Lysholm得分采用两样本均数t检验;采用Tegner运动评级进行膝关节功能评价。结果 纳入研究的40例膝关节软骨损伤患者均进入结果分析。40例膝关节软骨损伤患者手术前后膝关节功能Lysholm得分有差异(P<0.05)。40例膝关节软骨损伤患者手术后Tegner运动评级优15例,良20例,差5例,优良率87.5%。结论 微骨折术联合玻璃酸钠注射修复膝关节软骨损伤取得满意的治疗效果。关节镜下微骨折术联合玻璃酸钠注射修复操作方便,方法简单。不管是退变的膝关节软骨损伤还是外伤的软骨损伤,均可明显改善患者的关节功能和减轻疼痛症状。Objective To explore the clinical effect of arthroscopic microfracture surgery combined sodium hyaluronate injection to repair knee cartilage damage. Methods 40 patients who accept arthroscopic surgery in the Third People＇s Hospital of Hefei 2011-04/2012-09 were analyzed. There were 9 cases with traumatic cartilage injury. And 31 cases with knee cartilage damage caused by osteoarthritis. The defect area ranged from 0.5 cmz to 9 cmz ,with an average of 3.3 cmL Sodium hyaluronate （HA）20 mg was injected immediately after surgery,one week,two weeks and eight weeks after surgery. Knee function Lysholm score and Tegner movement rating were analyzed. Results The Lysholm score improved after surgery （P〈（0.05）. According to Tegner movement rating,there were excellent in 15 cases ;good in 20,poor in 5 eases. Excellent and good rate was87.5 %. Conclusion Microfracture surgery combined with sodium hyaluronate injection has satisfactory therapeutic effect to knee cartilage damage.

关 键 词：软骨损伤 关节镜 微骨折术 玻璃酸钠 

分 类 号：R684[医药卫生—骨科学]