胶原在止血材料中的应用  

The Application of Collagen in Hemostatic Materials

作　　者：宋强[1,2] 肖世维[1,2] 但年华[1,2] 李正军[1,2,3] 但卫华[1,2,3] 

机构地区：[1]四川大学制革清洁技术国家工程实验室,四川成都610065 [2]四川大学生物医学工程技术研究中心,四川成都610065 [3]四川大学苏州研究院,江苏苏州215000

出　　处：《西部皮革》2013年第4期8-14,共7页West Leather

基　　金：苏州市国际合作项目;项目编号:SH201108

摘　　要：胶原具有如高拉伸强度、生物相容性和低细胞毒性以及促进细胞增殖分化等特点,是一种具有良好性能的生物材料,作为生物止血材料一直是国内外研究的热点。本文以胶原止血材料的物理形态分类,分析了几类常见形态的胶原止血材料的制备及在动物、临床试验的应用评价,并展望了未来胶原止血材料的发展趋势。Collagen is a biomaterial with good and unique properties such as high tensile strength, biocompatibility and low cytotoxicity as well as capacity for promoting cell proliferation, and so on. As a hemostasis biomaterial, collagen is a hot research spot at home and abroad all the time. In this review collagen hemostasis materials were classified according to their physical shapes, and then the preparation technologies of several kinds of common collagen hemostatic materials and their evaluation for application in animal test and clinical test were analyzed. Finally, the future development trend of collagen hemostatic materials was prospected.

关 键 词：胶原 止血材料 生物医用材料 膜材料 

分 类 号：TS512[轻工技术与工程—皮革化学与工程]