蚊虫Wolbachia野外试验的研究进展  

Advancement of studies on utilizing mosquito Wolbachia in field experiment

作　　者：张东京[1] 梁格豪[2] 郑展图[2] 刘秀婷[2] 何石萍[2] 叶慧珍[2] 李卓雅[1] 詹希美[1] 郑小英[1] 

机构地区：[1]中山大学中山医学院寄生虫教研室,中山大学热带病研究教育部重点实验室,广州510080 [2]中山大学中山医学院临床医学院,广州510080

出　　处：《中国人兽共患病学报》2013年第2期183-186,共4页Chinese Journal of Zoonoses

基　　金：中山大学-密歇根州立大学联合基金(No.50000-7101022);2012年国家级大学生创新实验计划项目基金(No.20120558092)联合资助~~

摘　　要：沃尔巴克氏体(Wolbachia),该共生菌利用引起宿主产生细胞质不亲和(cytoplasmic incompatibility)而快速入侵野生宿主种群,或压制种群数量,或干扰RNA病毒在宿主体内复制,对人类、动物、环境和生物链没有影响,从而运用到防治登革热,这已被越来越多的科学家所认可。本文就近年来蚊虫Wolbachia野外试验技术条件、生物安全情况和存在问题与展望作一综述。Wolbachia can invade wild host population quickly via cytoplasmic incompatibility, which can suppress popu- lation size or interfere with RNA virus replication in their hosts. However, they have no influence on humans, animals, envi- ronment and biologic chain. More and more scientists are convinced that Wolbachia can be used to prevent dengue fever. This review is about the technical conditions of field experiment, the situation of biological safety and the existing problems and prospects by using Wolbachia.

关 键 词：WOLBACHIA 细胞质不亲和 野外试验 生物安全 

分 类 号：R375[医药卫生—病原生物学]