经直肠超声造影在前列腺良恶性结节鉴别诊断中的价值  

The Value of Contrast-enhancecd Transrectal Ultrasound in Diagnosis of Prostatic Benign and Malignant Nodules

作　　者：韩若凌[1] 叶卫华[1] 徐庆[1] 张平[1] 刘明瑜[1] 

机构地区：[1]河北医科大学第四医院超声科,石家庄市050011

出　　处：《中国超声医学杂志》2013年第2期164-166,共3页Chinese Journal of Ultrasound in Medicine

基　　金：河北省高校强势特色学科--第四医院肿瘤学支持项目(冀教高No.[2005]52);河北省科技厅课题(科学技术研究与发展计划No.0720611025D)

摘　　要：目的探讨经直肠实时超声造影在前列腺良恶性结节鉴别诊断中的价值。方法采用SonoVue造影剂,对21例患者40个前列腺结节行超声造影,观察病灶造影增强方式,绘制时间强度曲线(TIC),分析造影参数,比较前列腺良恶性结节之间的差异。结果 21例患者中良性结节组11例患者,恶性结节组10例,两组f-PSA、t-PSA比较差异均有统计学意义(P<0.05)。其中良性结节27个,恶性结节13个。良性结节超声造影增强方式以均匀增强方式为主,恶性结节增强早于周围正常组织,达峰强度、达峰时间及再灌注时间均短于良性结节(P<0.05),以不均匀增强为主。结论超声造影中前列腺良、恶性结节中的达峰强度、达峰时间及再灌注时间等参数有一定差异,有助于鉴别诊断。如将造影参数与f-PSA、t-PSA联合能进一步提高检出率。Objective To study the value of contrast enhanced transrectal ultrasound in diagnosis of prostatic be nign and malignant nodules. Methods A total of 21 patients with 40 prostatic nodules had contrast enhanced transree tal ultrasound examination, and the real time observation of dynamic perfusion and time intensity curve（TIC）were per formed, then the enhanced parameters to discrimination difference of prostatic benign and malignant nodoses were ana lyzed. Results The 21 patients were classified into two groups according to pathological results. 11 were benign and 10 were malignant. Both f PSA and t PSA comparison had significant differences（P〉0.05）. There were 27 benign and 13 malignant nodules. Peak intensity, time to peak and reperfusion time of the malignant nodules were all shorter than those of the benign nodules（P〈0.05）. Conclusions The difference of peak intensity, time to peak and reperfu sion time in diagnosis of prostatic benign and malignant nodules can conduce to differential diagnosis. To combine the contrast parameters, f-PSA and t PSA can raise the detect rate further.

关 键 词：经直肠超声 超声造影 前列腺 

分 类 号：R445.1[医药卫生—影像医学与核医学] R737.25[医药卫生—诊断学]