亚高原地区高血压与脂联素、瘦素、抵抗素的关系  

Correlation between hypertension and adiponcetin,leptin,and resistin in sub-plateau region

作　　者：李丽娟[1] 魏玲[2] 李琼[1] 

机构地区：[1]成都军区昆明总医院体检中心,昆明650032 [2]成都军区昆明总医院地干病房,昆明650032

出　　处：《西南国防医药》2013年第2期185-186,共2页Medical Journal of National Defending Forces in Southwest China

基　　金：云南省2009年社会发展科技计划项目(2009ZC147M)

摘　　要：目的了解昆明地区城镇高血压与血清脂联素、瘦素、抵抗素的关系。方法在2009年10月～2010年4月昆明城镇企事业单位到我院体检中心例行健康体检的18岁以上人群中,根据血压检测结果分为高血压和血压正常两组,对比分析两组人员的血清脂联素、瘦素、抵抗素检测结果。结果高血压组血清抵抗素、瘦素明显高于对照组,脂联素明显低于对照组(t=7.0、19.7、18.8,P<0.01)。结论昆明地区高血压发病与脂联素、瘦素、抵抗素有关,3种脂肪因子是高血压的危险因素;高血压预防应重视一级预防,控制体重可以预防由脂肪因子分泌及代谢的紊乱引发或加重的高血压,同时可据此探索新的治疗高血压的途径。Objective To study the correlation between high blood pressure and serum adiponcetin, leptin, and resistin in urban areas of Kunming city. Methods The subjects were people beyond 18 years old from enterprises and institutions in urban areas who received the routine health examination in our hospital from October 2009 to April 2010. They were divided into high blood pressure group and normal blood pressure group according to the examination results of their blood pressure. Comparison and analysis were made in the examination results of their serum adiponcetin,leptin, and resistin between the two groups. Results The levels of serum resistin and leptin in the high blood pressure group were significantly higher than those in the normal group, while the level of adiponcetin in the former group was significantly lower than that in the latter group （ t = 7.0,19.7,18.8, P 〈 0. 01 ）. Conclusion In Kunming city, the morbidity of hypertension is correlated with adiponcetin, leptin, and resistin, and they are the risk factors of hypertension. For the prevention of hypertension, it should be paid more attention to primary prevention. Weight control can prevent hypertension caused or aggravated by the secretion and metabolic disorders of adipo - cytokines. Furthermore, new ways of treatment on hypertension should be explored.

关 键 词：亚高原 高血压 脂联素 瘦素 抵抗素 相关性 

分 类 号：R544.1[医药卫生—心血管疾病]