老年患者腹部手术后BNP的变化及其与心力衰竭的关系探讨  

Investigation of B-type natriuretic peptide changes in geriatric patients and its relationship with heart failure after abdominal operation.

作　　者：李爱民[1] 刘金洪[1] 张鹏[1] 徐心[2] 李国威[2] 

机构地区：[1]航天中心医院普通外科,北京100049 [2]西安交通大学医学院附属西北医院普通外科,陕西西安710004

出　　处：《海南医学》2013年第3期345-346,共2页Hainan Medical Journal

摘　　要：目的探讨B型钠尿肽(BNP)在老年患者腹部外科手术后的变化情况及其与术后心力衰竭的关系。方法采用化学发光免疫法动态监测64例老年患者腹部手术后BNP水平的变化,并按术后BNP水平分组,观察各组患者心力衰竭发生的概率。结果 BNP水平≥400pg/ml的患者心力衰竭的发生概率较BNP水平<400pg/ml的患者明显升高;经积极治疗后BNP水平显著下降。结论老年患者腹部手术后BNP水平与心力衰竭的发生密切相关,动态监测BNP水平能有效防治老年患者腹部手术后心力衰竭。Objective To investigate the changes of B-type natriuretic peptide in geriatric patients after ab-dominal operation and its relationship with post-operational heart failure. Methods Using chemiluminescence immunoassay to monitor the levels of B-type natriuretie peptide in geriatric patients after abdominal operation, and to divide groups with its levels and observe the incidences of post-operational heart failure in different groups. Results The incidence of heart failure in patients with BNP levels above 400 pg/ml increased signifi- cantly than that in patients with BNP levels below 400 pg/ml. BNP level reduced significantly after effective treat-ment of heart failure. Conclusion The changes of B-type natriuretic peptide in geriatric patients after abdominal op-eration are closely related with post-operational heart failure. It is efficient to prevent heart failure in geriatric patients post abdominat operation by means of dynamically monitoring the changes of B-type natriuretie peptide.

关 键 词：B型钠尿肽 老年外科 心力衰竭 腹部手术 

分 类 号：R656[医药卫生—外科学]