氩激光治疗糖尿病视网膜病变264例观察  

Observation on Photocoagulation with Arqon for Treatment of 264 Cases of Diabetic Retinopathy

作　　者：包欣[1] 林菁[1] 谢田华[1] 朱靖[1] 史惠琴[1] 袁松涛[1] 

机构地区：[1]无锡市人民医院眼科,江苏无锡214000

出　　处：《现代生物医学进展》2012年第36期7147-7149,7029,共4页Progress in Modern Biomedicine

基　　金：国家自然科学基金项目(81070743)

摘　　要：目的:观察氩激光光凝治疗不同分期糖尿病视网膜病变(diabetic retinopathy,DR)的疗效。方法:对264例513眼DR患者按病变不同分期分别行黄斑格栅样光凝、次全视网膜光凝(sPRP)和全视网膜光凝(PRP)。随访3月-5年,观察患者视力、眼底及荧光血管造影情况。结果:总计有24.0%(123/513)的患眼视力得以上升,49.7%(255/513)视力保持不变,26.3%(135/513)视力下降。非增殖性DR激光治疗有效率为87.5%,增殖性DR有效率58.4%(P<0.05)。1型DM有效率43.5%,2型DM有效率81.4%(P<0.05)。结论:氩激光能有效控制DR,减缓DR患者视力的丧失,非增殖性DR疗效明显优于增殖性DR,2型DM疗效优于1型DM。Objective：To observe curative effect of photocoagulation with arqon on background diabetic retinopathy and proliferative diabetic retinopathy.Methods：We classified 513 eyes with 264 patients as background diabetic retinopathy and proliferative diabetic retinopathy with or not with cystoid macular edema.They were treated with grid patten photocoagulation,secondary panretinal photocoagulation（sPRP） and panretinal photocoagulation respectively.Followed up with visual acuity,ophthalmic fundus characteristics and fundus fluorescein angiography（FFA） for 3 months to 5 years.Results：Mean preoperative visual acuities and ophthalmic fundus characteristics were compared across groups.In all patients,visual acuity improved in 123 eyes（24 %）;was unchanged in 255 eyes（49.7 %）;and decreased in 135 eyes（26.3 %）.The effective rate of photocoagulation on nonproliferative diabetic retinopathy is 87.5 % compared with 58.4 % on proliferative diabetic retinopathy（P0.05）,43.5 % on type 1 diabetes mellitus compared with 81.4 % on type 2 diabetes mellitus.Conclutions：Photocoagulation with arqon can effectively restrain the decrease of visual acuity especially in prolifera-tive diabetic retinopathy patients with type 2 diabetes mellitus.

关 键 词：氩激光 糖尿病视网膜病变 治疗 

分 类 号：R587.2[医药卫生—内分泌]