某三级甲等医院住院高血压患者抗高血压药应用分析  

Utilization of Antihypertensive Drugs in The Inpatients of A Three-A Level Hospital

作　　者：徐锦华[1] 潘雯[2] 宫建[3] 王东侠[1] 任莉娜[4] 佟利剑[5] 王国锋[6] 汪立杰[6] 李福生[7] 李丹[7] 孙永发[8] 

机构地区：[1]北京市丰台区长辛店医院,北京100072 [2]辽宁省疾病预防控制中心,沈阳110005 [3]沈阳药科大学生命科学与生物制药学院临床药学教研室,沈阳110016 [4]中国医科大学附属第一医院心内科,沈阳110001 [5]沈阳二四二医院心血管内科,沈阳110034 [6]中国医科大学附属第四医院心内科,沈阳110032 [7]辽宁省人民医院,沈阳110016 [8]卫生部卫生发展研究中心,北京100191

出　　处：《中国医院用药评价与分析》2012年第11期996-999,共4页Evaluation and Analysis of Drug-use in Hospitals of China

摘　　要：目的:了解某三级甲等医院住院高血压患者抗高血压药的应用情况,为临床用药提供参考。方法:采取分层随机抽样方法,选定沈阳市一所三级甲等医院,随机抽取2010年3月—2012年4月住院高血压患者200例,提取病历中抗高血压药应用信息,计算抗高血压药的用药频率(DDDs)、限定日费用(DDC)及药物利用指数(DUI)。结果:抗高血压药使用例次最高的药品为美托洛尔;DDDs排序居前3位的药品分别为硝苯地平、咪达普利、替米沙坦;DDC排序居前3位的药品分别为艾司洛尔、贝尼地平、阿罗洛尔;DUI接近1的药品为氨氯地平、缬沙坦和阿罗洛尔。结论:某三级甲等医院住院高血压患者抗高血压药应用情况较好,但个别药物存在不合理应用现象。OBJECTIVE：To investigate the utilization of antihypertensive drugs in the inpatients with hypertension in a three-A level hospital for clinical reference of rational drug use.METHODS：By a stratified random sampling,a total of 200 hospitalized patients with hypertension were randomly selected from a three-A hospital in Shenyang from March 2010 to April 2012,with the utilization data of antihypertensive drugs extracted from medical records for analysis with regard to DDDs,DDC and drug utilization index（DUI）.RESULTS：Metoprolol took the lead in terms of frequency of use.Esmolol,benidipine and aronixil dominated the first 3 places in terms of DDDs.The drug utilization index（DUI） for amlodipine,valsartan,and arotinolol were approximately equal to 1.CONCLUSION：The utilization of antihypertensive drugs for the inpatients with hypertension in this three-A hospital level was rational on the whole;however,certain antihypertensive drug was used irrationally.

关 键 词：抗高血压药 住院患者 用药频度 限定日费用 药物利用指数 

分 类 号：R972.4[医药卫生—药品]