362例Ⅰ类切口围术期预防性应用抗菌药物合理性分析  

Rationality of Perioperative Use of Prophylactic Antibiotics in Patients Undergoing TypeⅠ Incision Operation:Analysis of 362 Cases

作　　者：刘晓敏[1] 陈亮[1] 王旭[1] 石丽霞[1] 张雷[1] 

机构地区：[1]吉林医药学院附属医院,吉林吉林132013

出　　处：《中国医院用药评价与分析》2012年第11期1002-1004,共3页Evaluation and Analysis of Drug-use in Hospitals of China

摘　　要：目的:了解某院Ⅰ类切口围术期预防性应用抗菌药物的合理性,为促进临床合理使用抗菌药物提供参考。方法:采用回顾性调查方法,对某院2010年10月—2011年4月出院的362份Ⅰ类切口手术病历进行统计分析。结果:某院Ⅰ类切口围术期抗菌药物预防性应用抗菌药物者为340例,其中有用药指征的184例,占50.83%;术前0.5～2 h给药的8例,占2.21%;术中全未追加药物,总预防用药时间超过48 h的317例,占93.23%;使用排序居前3位的药品分别为头孢替唑、头孢西丁、替硝唑;单一用药259例(占71.55%),二联用药81例(占22.38%)。结论:某院Ⅰ类切口围术期预防性应用抗菌药物存在不合理现象,主要表现为无指征用药、首次用药时间不当、疗程过长、选药不当等,需加强管理。OBJECTIVE：To investigate the rationality of the perioperative use of prophylactic antibacterial drugs in patients undergoing typeⅠincision operation in a hospital for reference of rational use of antibacterial drugs.METHODS：In a retrospective survey,the medical records of a total of 362 patients undergoing typeⅠincision discharged from a hospital between Oct.2010 and Apr.2011 were analyzed statistically.RESULTS：340 cases had perioperative use of prophylactic antibacterial drugs,with 184（50.83%） had indications for medication;8 cases received antibiotics 0-2 hours before operation,none received antibiotics during operation;317 cases（93.23%） used prophylactic antibiotics for a course of more than 48 hours.Ceftezole,cefoxitin and tinidazole were the top 3 antibacterial drugs in consumption.259（71.55%） used one antibiotic while 81（22.38%） used two concurrently.CONCLUSION：The perioperative use of prophylactic antibacterial drugs in patients undergoing typeⅠincision operation in this hospital is irrational including drug use in the absence of medication indications,improper initial administration time,prolonged course of treatment and irrational choice of drugs etc,thus measures should be taken to tighten control on the antibiotic use.

关 键 词：Ⅰ类切口 围术期 抗菌药物 

分 类 号：R978.1[医药卫生—药品]